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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 7 of 7 results

Project Title
Project Status
Project Type

Comparing Abatacept to Usual Care for Preventing Disease Worsening in Juvenile Idiopathic Arthritis

Duke University
| North Carolina
Laura Schanberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression (CEPIO-D)

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways for Patients and Clinics to Improve Blood Pressure Control

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatments for Patients with Inflammatory Bowel Disease Who Don't Respond to Anti-TNF Therapy

The University of North Carolina at Chapel Hill^
| North Carolina
Michael Kappelman, MD, MPH^
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Treatments for Older Adults Who Have Major Depression That Does Not Respond to First-Line Antidepressant Medicines -- The OPTIMUM Study

Washington University School of Medicine
| Missouri
Eric Juckeland Lenze, MD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing ECT and Ketamine in Adults with Treatment-Resistant Depression – The ELEKT-D Study

Cleveland Clinic Foundation
| Ohio
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research

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