Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 28 results

Project Title
Project Status
Project Type

Care in the CCP Program versus Care in the C4P Program versus Care in Traditional Care Coordinator Program

The University of Chicago
| Illinois
David O. Meltzer, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat People with PTSD and Substance Use Disorder -- The COMPASS Study

Center for Veterans Research and Education
| Minnesota
Shannon M. Kehle-Forbes, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Approaches to Care Coordination for Patients with Multiple Health Needs

HealthPartners Institute
| Minnesota
Leif I. Solberg, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Ways to Treat Anxiety in Youth

Children's Hospital Los Angeles
| California
Bradley S. Peterson, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Admit Children to Hospitals

Dartmouth-Hitchcock Clinic^
| New Hampshire
JoAnna Leyenaar, MD, MPH, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospital
| California
Katie Stone, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Improve Dialysis Session Stability

University of Michigan
| Michigan
Tiffany Veinot, MLIS, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Testing Whether Providing Older Patients with a List of Questions to Ask Their Surgeons Improves Decision Making and Well-Being

University of Wisconsin-Madison
| Wisconsin
Margaret L. Schwarze, MD, MPP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Oral Medicines to Treat Hepatitis C Virus -- The PRIORITIZE Study

University of Florida
| Florida
David Robert Nelson, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Patient-Centered Hepatitis C Virus Care for People Who Inject Drugs -- The HERO Study

Clemson University^
| South Carolina
Alain Litwin, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Testing a Program That Provides Care for Urgent Health Problems at Home Instead of the Emergency Room

Massachusetts General Hospital
| Massachusetts
Lisa I. Iezzoni, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity

Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effects of How Often Men Have PSA Testing in the First Year after Prostate Cancer Treatment

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Ronald C. Chen, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Approaches That Clinics Can Use to Help Control High Blood Pressure among Black Patients

The University of Alabama at Birmingham
| Alabama
Andrea L. Cherrington, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study

Kaiser Permanente Washington Health Research Institute^
| Washington
David Arterburn, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Prevent Blood Clots in Patients Who Have Hip or Knee Replacement Surgery -- The PEPPER Study

Dartmouth-Hitchcock Clinic^
| New Hampshire
Vincent Domenic Pellegrini, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Testing a Program to Improve the Integration of Behavioral Health Care into Primary Care Settings

University of Vermont and State Agriculture College
| Vermont
Benjamin Littenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Low-Dose versus High-Dose Aspirin to Prevent Problems from Heart Disease -- The ADAPTABLE Study -- A PCORnet® Study

Duke University
| North Carolina
William Schuyler Jones, MD*
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Testing a Program to Improve Patient-Clinician Communication for Patients Who Speak Limited English

University of California San Francisco
| California
Leah S. Karliner, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

A Training Program on Pain Coping Skills for African Americans with Hip or Knee Arthritis

The University of North Carolina at Chapel Hill
| North Carolina
Kelli Allen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Bladder Management Strategies for People with Spinal Cord Injuries

University of Utah
| Utah
Jeremy Myers, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Changes in Health for Patients Who Complete Treatment for Chronic Hepatitis C Virus -- The PROP up TARGET Study

The University of North Carolina at Chapel Hill
| North Carolina
Donna Evon, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing an Online Program with and without Health Management Support to Help Patients Manage Their Weight

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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