Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 61 results

Project Title
Project Status
Project Type

Preventing Suicidal Behavior with Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University
| Maryland
Holly Wilcox, PhD, MA
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Prevent Falls among Patients with Cirrhosis of the Liver

University of Michigan
| Michigan
Elliot Tapper, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Types of Medicine for Pain after Surgery -- The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing How Well Different Diabetes Medicines Reduce the Risk of Heart Disease

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Romain Neugebauer, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients Who Are at Risk for Heart Disease

Mayo Clinic
| Minnesota
Rozalina McCoy, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

The University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat PTSD among Veterans

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Keith Bredemeier, PhD, BA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Types of Well-Child Visits for Preventing Obesity among Preschool-Aged Children in Rural Areas

Geisinger Clinic
| Pennsylvania
Lisa Bailey-Davis, RD, DEd
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Manage Pain after High-Dose Chemotherapy

Memorial Sloan-Kettering Cancer Center
| New York
Gary Deng, MD, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Standard and Family Diabetes Self-Management Education for Improving Diabetes Outcomes

University of Arkansas for Medical Sciences
| Arkansas
Pearl A. McElfish, PhD, MBA
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospital
| California
Katie Stone, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Meditation versus Medicine for Patients with Anxiety Disorders

Georgetown University Medical Center
| District of Columbia
Elizabeth Hoge, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Identify Sleep Apnea in People with Traumatic Brain Injury during Inpatient Rehabilitation

Tampa VA Research and Education Foundation
| Florida
Risa Nakase-Richardson, PhD, FACRM, FNAN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Treating Genital Herpes during Pregnancy Improve Birth Outcomes?

Kaiser Foundation Research Institute
| California
De-Kun Li, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Medications Added to a Serotonin Reuptake Inhibitor to Treat Patients with PTSD

University of California San Francisco
| California
Beth Cohen, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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