Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 99 results

Project Title
Project Status
Project Type

Implementation of Symptom Monitoring with Electronic Patient-Reported Outcomes (ePROs) During Cancer Treatment: The OncoPRO Initiative

The University of North Carolina at Chapel Hill
| North Carolina
Ethan Basch, M.D., MPhil, M.S.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Putting a Depression Screening and Treatment Program in Place for Patients on Dialysis

University of Washington
| Washington
Rajnish Mehrotra, M.D., M.S.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Supporting the Use of a Treatment Approach in Health Systems to Improve Outcomes for Adults with Moderate to Severe Asthma

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, M.D.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Disseminating New Evidence to Prevent Blood Clots in Patients with Bone Fractures

University of Maryland Baltimore
| Maryland
Nathan O'Hara, PhD, MHA
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Promoting Shared Decision Making for Decisions about Treatment of Severe Aortic Stenosis

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Promoting Informed Decision Making When Choosing between Antibiotics or Surgery for Appendicitis -- The TRIAD (Treatment Individualized Appendicitis Decision Making) Implementation Program

University of Washington
| Washington
David Flum, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Using a Smartphone Program to Help Patients Manage Symptoms of Serious Mental Illness

University of Washington
| Washington
Dror Ben-Zeev, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Supporting Pain Management for Sickle Cell Disease Crisis at Infusion Centers

Johns Hopkins School of Medicine
| Maryland
Sophie Lanzkron, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Matching of Patients to Mental Healthcare Therapists’ Strengths

University of Massachusetts Amherst
| Massachusetts
Michael Constantino, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Putting an Online Weight Management Program in Place in Clinical and Community Settings

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Expanding the Use of Reports That Capture Age-Related Problems to Improve Doctor-Patient Conversations in Community Cancer Clinics

The University of Texas MD Anderson Cancer Center
| Texas
Lisa Lowenstein, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Expanding the Use of an End-of-Life Care Planning Program for Patients with Kidney Disease

The George Washington University School of Nursing
| Virginia
Dale Lupu, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Expanding Use of the Health-E You/Salud iTu Mobile App to Promote Birth Control Use among Teens

The Regents of the University of California, San Francisco
| California
Kathleen Tebb, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Uptake of a Self-Care Program for Patients with Acute Heart Failure After Discharge from the Emergency Department

Vanderbilt University Medical Center
| Tennessee
Sean P. Collins, MD, MSc
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing How Well Different Diabetes Medicines Reduce the Risk of Heart Disease

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Romain Neugebauer, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients Who Are at Risk for Heart Disease

Mayo Clinic
| Minnesota
Rozalina McCoy, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Supporting Families' Treatment Decisions with Evidence on Treatment of Urea Cycle Disorders

Children's National Health System
| District of Columbia
Nicholas Ah Mew, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Dissemination Project (Limited Competition D&I PFA)

Expanding Effective Home Oxygen Management Strategies for Premature Infants

University of Massachusetts Medical School
| Massachusetts
Lawrence Rhein, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Best-Practice, Patient-Centered Venous Thromboembolism (VTE) Prevention in Trauma Centers

Coalition for National Trauma Research
| Texas
Elliott Haut, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Expanding the Use of a School-Based Program to Improve Executive Functioning among Students with Symptoms of Autism Spectrum Disorder or Attention Deficit/Hyperactivity Disorder

University of Colorado Denver
| Colorado
Laura G. Anthony, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Using a Learning Collaborative to Help Hospitals Support Patient Decisions about Orthopedic Care

Massachusetts General Hospital
| Massachusetts
Karen R. Sepucha, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Team-based Outpatient Palliative Care in Parkinson Foundation Centers of Excellence

University of Rochester
| New York
Benzi M. Kluger, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Two Ways to Reduce Medicine Use among Older Patients with Type 2 Diabetes

Kaiser Foundation Hospitals
| California
Richard W. Grant, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

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