Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 18 of 18 results

Project Title
Project Status
Project Type
Has Results

Testing the Effectiveness of a Text-Message-Based Home Monitoring Program and Oxygen Monitoring for Patients with COVID-19 -- The COVID Watch Study

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Kit Delgado, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Acupuncture and Massage to Treat Pain in Patients with Advanced Cancer -- The IMPACT Study

Memorial Sloan Kettering
| New York
Jun J. Mao, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Applying Results from Randomized Controlled Trials to Patients in Clinical Practice Using Hybrid Study Methods

The University of North Carolina at Chapel Hill
| North Carolina
Jennifer L. Lund, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Depression among Patients with Advanced Heart Failure

Cedars-Sinai Health System
| California
Waguih William IsHak, MD, FAPA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Medicines to Treat Ulcerative Colitis and Crohn's Disease When Anti-TNF Medicines Don't Work

The University of North Carolina at Chapel Hill^
| North Carolina
Michael D. Kappelman, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Meditation versus Medicine for Patients with Anxiety Disorders

Georgetown University Medical Center
| District of Columbia
Elizabeth Hoge, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Antiseptic Skin Solutions to Prevent Infection in Patients Having Surgery to Treat Fractures -- The PREPARE Study

University of Maryland, Baltimore
| Maryland
Gerard P. Slobogean, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Mobile Stroke Unit Treatment with Emergency Room Care among Patients Who Have Had a Stroke -- The BEST-MSU Study

Memorial Hermann-Texas Medical Center
| Texas
James Grotta, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Treatment Approaches for Older Adults with Treatment-Resistant Depression -- The OPTIMUM Study

Washington University School of Medicine
| Missouri
Eric J. Lenze, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study

Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Decrease Severe Asthma Attacks among Black and Latinx Adults with Moderate to Severe Asthma -- The PREPARE Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Patient-Centered Hepatitis C Virus Care for People Who Inject Drugs -- The HERO Study

Clemson University^
| South Carolina
Alain Litwin, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Stopping or Continuing Use of Disease Modifying Therapies in Older Adults with Multiple Sclerosis -- The DISCOMS Trial

University of Colorado Denver
| Colorado
John R. Corboy, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Medicines to Treat Crohn’s Disease in Children and Adolescents -- The COMBINE Trial

The University of North Carolina at Chapel Hill
| North Carolina
Michael D. Kappelman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

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