Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 45 results

Project Title
Project Status
Project Type
Has Results

Evaluating Therapies to Prevent Future Stroke in Patients with Patent Foramen Ovale-Related Strokes -- The SCOPE Study

Tufts Medical Center Inc.
| Massachusetts
David M. Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Care in the CCP Program versus Care in the C4P Program versus Care in Traditional Care Coordinator Program

The University of Chicago
| Illinois
David O. Meltzer, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat People with PTSD and Substance Use Disorder -- The COMPASS Study

Center for Veterans Research and Education
| Minnesota
Shannon M. Kehle-Forbes, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

New Methods to Analyze Data from Cluster Randomized Trials when Clusters Differ after Treatment Assignment

Duke University
| North Carolina
Fan Li, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Approaches to Care Coordination for Patients with Multiple Health Needs

HealthPartners Institute
| Minnesota
Leif I. Solberg, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Programs for Managing Hearing Loss among Older Adults in Assisted Living Facilities

University of Pittsburgh
| Pennsylvania
Catherine Palmer, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Ways to Treat Anxiety in Youth

Children's Hospital Los Angeles
| California
Bradley S. Peterson, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Anxiety Disorders among Children and Adolescents

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
John T. Walkup, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Obtain Hearing Aids for People with Age-Related Hearing Loss

Northwestern University
| Illinois
Sumitrajit Dhar, PhD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research

Toward a New Generation of Matching Methods for Comparative Effectiveness Research

Harvard Medical School
| Massachusetts
Jose R. Zubizarreta, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Developing Methods to Improve the Accuracy of Data Obtained from Clinicians' Notes in Electronic Health Records

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Reduce Medicine Use among Older Patients with Type 2 Diabetes

Kaiser Foundation Hospitals
| California
Richard W. Grant, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Primary Care Treatment Options for People with PTSD

University of Washington
| Washington
John Fortney, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Developing Methods for Planning and Analyzing Stepped-Wedge Cluster Randomized Trials

University of North Carolina at Chapel Hill
| North Carolina
John S. Preisser, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Improve Communication between Healthcare Teams and People with a Communication Disability

University of Colorado Denver
| Colorado
Megan A. Morris, PhD, MPH, CCC-SLP
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Three Ways to Start Taking Medicine for Opioid Use Disorder

University of Colorado Anschutz Medical Campus
| Colorado
Linda Zittleman, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Types of Well-Child Visits for Preventing Obesity among Preschool-Aged Children in Rural Areas

Geisinger Clinic
| Pennsylvania
Lisa Bailey-Davis, RD, DEd
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Manage Pain after High-Dose Chemotherapy

Memorial Sloan-Kettering Cancer Center
| New York
Gary Deng, MD, PhD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Cervical Ripening in the Outpatient Setting: A Systematic Review

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Radiation Therapy for Brain Metastases: A Systematic Review

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Interventions for Breathlessness in Patients With Advanced Cancer: A Systematic Review

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Improving Methods for Extracting Data from Clinicians' Notes in Electronic Health Records

Medical University of South Carolina
| South Carolina
Paul M. Heider, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center, Inc
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

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