Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 15 of 15 results

Project Title
Project Status
Project Type

Thriving Hearts: Healing-Centered, Integrated, Community Maternity Care

The University of North Carolina at Chapel Hill
| North Carolina
Alison Stuebe, B.S., M.D., MSc
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Implementation of Symptom Monitoring with Electronic Patient-Reported Outcomes (ePROs) During Cancer Treatment: The OncoPRO Initiative

The University of North Carolina at Chapel Hill
| North Carolina
Ethan Basch, M.D., MPhil, M.S.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Duke University Health System HSII Capacity Building Project

Duke University Health System
| North Carolina
Project Status:
Ongoing
Project Type:
Health Systems Implementation Initiative (HSII)

Atrium Health HSII Capacity Building Project

Atrium Health
| North Carolina
Project Status:
Ongoing
Project Type:
Health Systems Implementation Initiative (HSII)

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

The HERO Research Program -- A PCORnet® Project to Support Studies on COVID-19

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Re-Think the Strip: Stopping Glucose Monitoring for Non-Insulin Treated Type 2 Diabetes

The University of North Carolina at Chapel Hill
| North Carolina
Katrina Donahue, MD, MPH
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Abatacept to Usual Care for Preventing Disease Worsening in Juvenile Idiopathic Arthritis

Duke University
| North Carolina
Laura Schanberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Medicines to Treat Ulcerative Colitis and Crohn's Disease When Anti-TNF Medicines Don't Work

The University of North Carolina at Chapel Hill^
| North Carolina
Michael D. Kappelman, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

A Shared Decision Making Intervention for Children with Asthma in the Emergency Room

Carolinas Medical Center
| North Carolina
Hazel Tapp, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

PCORnet Coordinating Center Phase II (Duke University)

Duke University
| North Carolina
Adrian F. Hernandez, MD, MHS and Richard Platt, MD, MSc
Project Status:
Completed
Project Type:
PCORnet® Coordinating Center Phase II
Has Results

Comparing the Safety and Effectiveness of Low-Dose versus High-Dose Aspirin to Prevent Problems from Heart Disease -- The ADAPTABLE Study -- A PCORnet® Study

Duke University
| North Carolina
William Schuyler Jones, MD*
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Safety and Effectiveness of Medicines to Treat Crohn’s Disease in Children and Adolescents -- The COMBINE Trial

The University of North Carolina at Chapel Hill
| North Carolina
Michael D. Kappelman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

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