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Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 21 of 21 results

Project Title
Project Status
Project Type

Semantic Data Quality Standards for Multi-Center Clinical Research Studies and Networks

Children's Hospital of Philadelphia
| Pennsylvania
Charles Bailey, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Monitor and Treat High Blood Pressure in Children with Chronic Kidney Disease -- The PRESERVE Study

Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Development of Methods to Improve Identification of Patients with Rare or Complex Diseases

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Daniel Herman, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Treat Children with Inactive Spondyloarthritis -- The BACK-OFF JSpA Study

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

The HERO Research Program -- A PCORnet® Project to Support Studies on COVID-19

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Improving Antibiotic Prescribing in Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Developing Methods to Identify Patients Who Benefit Most from Different Treatments

University of Pennsylvania
| Pennsylvania
Yong Chen, PhD, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatments for Patients with Inflammatory Bowel Disease Who Don't Respond to Anti-TNF Therapy

The University of North Carolina at Chapel Hill^
| North Carolina
Michael Kappelman, MD, MPH^
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

PCORnet Coordinating Center Phase II (Duke University)

Duke University
| North Carolina
Adrian F. Hernandez, MD, MHS and Richard Platt, MD, MSc
Project Status:
In progress; Recruitment not applicable
Project Type:
PCORnet® Coordinating Center Phase II
Has Results

Assessing the Effects of Intensive Behavioral Therapy on Weight Loss among Patients with or at Risk for Type 2 Diabetes

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Jennifer Kraschnewski, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatments for Children with Crohn's Disease -- The COMBINE Trial

The University of North Carolina at Chapel Hill
| North Carolina
Michael Kappelman, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Reduce Bone Fractures and Injuries among Older Adults Who Have Fallen -- The WISE Study

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Christopher Sciamanna, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Treat Low Back Pain and Prevent Chronic Pain and Disability -- The TARGET Trial

University of Pittsburgh
| Pennsylvania
Anthony Delitto, PhD, PT, FAPTA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

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