Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 70 results

Project Title
Project Status
Project Type

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Sinusitis

Georgetown University Medical Center
| District of Columbia
Daniel Merenstein, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research

Does Omitting Stent Placement Improve Pain among Patients with Kidney Stones? -- The SOUL MUSIC Study

University of Michigan Medical School, Department
| Michigan
Khurshid Ghani, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Urgency Urinary Incontinence in Women -- The BEST Trial

Women and Infants Hospital-Rhode Island
| Rhode Island
Vivian Sung, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Tailoring Incontinence Care: OnabotulinumtoxinA for Urgency Urinary Incontinence Among Older Women

Dartmouth-Hitchcock Clinic
| New Hampshire
Anne Cooper, MD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Manage Care for Urinary Incontinence

University of California San Diego
| California
Jennifer Anger, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Using a Virtual Screening and Care Program to Increase Access to Treatment for Urinary Incontinence in Women

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Brian Mittman, PhD, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Comparing Two Ways to Follow Up after a Child Goes Home from the Hospital -- The FAAN-C Trial

University of Utah
| Utah
Eric Coon, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Does Treating Genital Herpes in Pregnancy Reduce Racial Disparities in Severe Maternal Morbidity? -- The PCORI SMM Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
De-Kun Li, MD, MPH, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Improve COVID-19 Vaccination Rates at Long-Term Care Centers -- The ENSPIRE Study

Kaiser Foundation Health Plan of Washington (Kaiser Permanente Washington Health Research Institute)
| California
Clarissa Hsu, PhD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Increase Confidence in COVID-19 Vaccines among Long-Term Care Workers -- The CONFIDENT Trial

Trustees of Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, MSc
Project Status:
In progress; Data collected
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Treatment for Opioid Use Disorder before and during the COVID-19 Pandemic

Boston VA Research Institute, Inc.
| Massachusetts
Nicholas Livingston, PhD and Risa Weisberg, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Telehealth and In-Person Care for Patients with Chronic Conditions

Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Programs to Train Staff to Reduce the Spread of COVID-19 in Nursing Homes

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Jennifer L. Kraschnewski, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing How State and Local COVID-19 Policies Affect Patient-Reported Outcomes

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Protecting the Well-Being of Healthcare Workers during the COVID-19 Pandemic -- The COVER-HCW Project

RAND Corporation
| California
Lisa S. Meredith, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparative Effectiveness of Single-Site and Scattered-Site Permanent Supportive Housing on Patient-Centered and COVID-19 Related Outcomes for People Experiencing Homelessness

University of Southern California
| California
Benjamin Henwood, PhD, MA, MSW
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Testing the Effectiveness of a Text-Message-Based Home Monitoring Program and Oxygen Monitoring for Patients with COVID-19 -- The COVID Watch Study

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Kit Delgado, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Deliver Remote Mental Health Support during the COVID-19 Pandemic

The Research Foundation For The State University of New York
| New York
Yu-Ping Chang, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Programs to Decrease HIV Risk among African-Born Black Women

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Bisola Ojikutu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Improve Pre-Exposure Prophylaxis (PrEP) Use for HIV Prevention

Public Health Foundation Enterprises, Inc.
| California
Albert Liu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Monitor Patients with Multiple Chronic Conditions after They Return Home from the Hospital for an Infection -- The ACCOMPLISH Study

UPMC Center for High ValueHealth Care
| Pennsylvania
Dr. Kalpana Char, MD*
Project Status:
In progress; Recruiting
Project Type:
Research

Improving Antibiotic Prescribing in Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

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