Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 19 of 19 results

Project Title
Project Status
Project Type

Comparing Two Ways to Help Patients Control High Blood Pressure

Brody School of Medicine at East Carolina University
| North Carolina
Doyle Cummings, PharmD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Monitor Symptoms from Dialysis -- The SMaRRT-HD Trial

The University of North Carolina at Chapel Hill
| North Carolina
Jennifer Flythe, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Four Ways to Reduce Pregnancy Complications among Black Mothers -- The ACURE4Moms Study

University of North Carolina at Chapel Hill School of Medicine
| North Carolina
Jennifer Tang, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Testing Two Ways to Increase Receipt of Early Kidney Transplants among Patients with Kidney Failure

Duke University
| North Carolina
Leigh Ebony Boulware, MD, MPH, FACP
Project Status:
In progress; Recruiting
Project Type:
Research

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Abatacept to Usual Care for Preventing Disease Worsening in Juvenile Idiopathic Arthritis

Duke University
| North Carolina
Laura Schanberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Testing a Standard Approach to Match Patients with Addiction to Treatment Based on Their Needs -- The PCAST Study

RTI International
| North Carolina
Tami L. Mark, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Transitional Care for Teens and Young Adults with Sickle Cell Disease with and without Peer Mentoring

Atrium Health
| North Carolina
Payal Desai
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Ways to Encourage and Improve End-of-Life Care Planning

Duke University
| North Carolina
Kimberly Johnson, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Two Programs for Helping Patients Make Informed Decisions about Rheumatoid Arthritis Treatment

The University of North Carolina at Chapel Hill
| North Carolina
Susan Blalock, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Low-Dose versus High-Dose Aspirin to Prevent Problems from Heart Disease -- The ADAPTABLE Study -- A PCORnet® Study

Duke University
| North Carolina
William Schuyler Jones, MD*
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Testing a Program to Help Patients Prepare for Kidney Failure Treatment -- The PREPARE NOW Study

Duke University
| North Carolina
Leigh E. Boulware, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing a Care Program and Usual Care to Help Patients Transition Home from the Hospital after a Stroke -- The COMPASS Study

Wake Forest University
| North Carolina
Pamela W. Duncan, PhD, PT
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Physical Therapy, Internet-Based Exercise Training, and No Therapy for Knee Osteoarthritis

University of North Carolina Chapel Hill^
| North Carolina
Kelli D. Allen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Aortic Valve Disease

Duke University
| North Carolina
J. Matthew Brennan, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Daily Self-Monitoring of Blood Sugar Levels Improve Blood Sugar Control and Quality of Life for Patients with Type 2 Diabetes Who Do Not Use Insulin? -- The Monitor Trial

University of North Carolina Chapel Hill
| North Carolina
Katrina Donahue, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can Coping-Skills Training Help Patients Who Have Received Intensive Hospital Care to Cope with Depression and Anxiety?

Duke University
| North Carolina
Christopher Ethan Cox, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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