Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 23 of 23 results

Project Title
Project Status
Project Type

Annual Wellness Visits versus GRACE-augmented Annual Wellness Visits for Older Adults with High Needs

Massachusetts General Hospital
| Massachusetts
Christine Ritchie, M.D., MSPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Measurement Matters: Refining and Validating a Patient-Centered Outcomes Research Engagement Measure

University of Massachusetts Boston
| Massachusetts
Marc Cohen, Ph.D., M.A.
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Learning to Predict Disease Trajectories

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Mei-Sing Ong, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Identification of Temporal Data Patterns Predictive of Adverse Outcomes in Patients with Diabetes

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing How State and Local COVID-19 Policies Affect Patient-Reported Outcomes

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Systematic, Collaborative, PFO closure Evaluation (SCOPE) Study Conference: Research-Related Conference Support Award

Tufts Medical Center
| Massachusetts
David M. Kent, MD, MS
Project Status:
Awarded; In progress
Project Type:
Engagement in Research, Engagement Award Conference: Evidence Synthesis
Has Results

Developing Methods to Improve the Accuracy of Data Obtained from Clinicians' Notes in Electronic Health Records

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Multi-stakeholder Engagement for Enabling Patient-Driven Research

Accelerated Cure Project for Multiple Sclerosis
| Massachusetts
Robert McBurney, BSc, PhD
Project Status:
Completed
Project Type:
PPRN Limited Competition Award

An Open-Source Crowdsourcing Platform for Community-Engaged Research and Dissemination

Board of Trustees of the Leland Stanford Junior University
| California
Mitchell R. Lunn, MD, MAS
Project Status:
Completed
Project Type:
PPRN Limited Competition Award

PARTNERS - Enabling Real-time, Personalized Engagement in Research: An App-based Approach

Boston Children's Hospital
| Massachusetts
Marc Natter, MD
Project Status:
Completed
Project Type:
PPRN Limited Competition Award

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospital
| California
Katie Stone, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Identify and Provide Care to Patients at Risk for Hereditary Cancer

Kaiser Foundation Research Institute
| California
Douglas Corley, MD, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression (CEPIO-D)

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Train Healthcare Clinic Staff to Ask Patients about Sexual Orientation and Gender Identity

Fenway Community Health Center
| Massachusetts
Kenneth H. Mayer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Approaches to Advance Care Planning for Patients with Advanced Illness

Regents of the University of California, Los Angeles
| California
Neil S. Wenger MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Identifying Barriers to Telehealth Home-Based Palliative Care for Patients with Serious Illness -- The HomePal Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Huong Q. Nguyen, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Standard and Short Online Mindfulness Therapy Programs for Improving Well-Being -- The Healthy Mind Healthy You Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Improve Depression Symptoms among Adults who Identify as LGBTQ+ -- The RADD Study

University of California, Los Angeles
| California
Bowen Chung, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Three Ways to Increase Physical Activity in Patients with Depression and Cardiovascular Disease -- The Healthy Hearts Healthy Minds Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Looking at the Effects of Antibiotic Use on Childhood Obesity and Growth -- The PCORnet® Antibiotics Study

Harvard Pilgrim Health Care, Inc.
| Massachusetts
Jason Block, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

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