Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 73 results

Project Title
Project Status
Project Type

Does Omitting Stent Placement Improve Pain among Patients with Kidney Stones? -- The SOUL MUSIC Study

University of Michigan Medical School, Department
| Michigan
Khurshid Ghani, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Urgency Urinary Incontinence in Women -- The BEST Trial

Women and Infants Hospital-Rhode Island
| Rhode Island
Vivian Sung, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Tailoring Incontinence Care: OnabotulinumtoxinA for Urgency Urinary Incontinence Among Older Women

Dartmouth-Hitchcock Clinic
| New Hampshire
Anne Cooper, MD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Manage Care for Urinary Incontinence

University of California San Diego
| California
Jennifer Anger, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Using a Virtual Screening and Care Program to Increase Access to Treatment for Urinary Incontinence in Women

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Brian Mittman, PhD, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Comparing Two Ways to Follow Up after a Child Goes Home from the Hospital -- The FAAN-C Trial

University of Utah
| Utah
Eric Coon, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Screening Tests for Colon Cancer in Older Adults with a History of Colon Polyps -- The COOP Study

Dartmouth-Hitchcock Clinic
| New Hampshire
Audrey Calderwood, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Treatments for Children with Lennox-Gastaut Syndrome

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Sandi Lam, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Does Receiving Guidelines-Based Care Improve Health Outcomes for Adults with Congenital Heart Defects? -- The CHI-RON Study

Louisiana Public Health Institute
| Louisiana
Thomas Carton, PhD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Supporting Families' Treatment Decisions with Evidence on Treatment of Urea Cycle Disorders

Children's National Health System
| District of Columbia
Nicholas Ah Mew, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Dissemination Project (Limited Competition D&I PFA)

Comparing Three Ways to Treat Children with Inactive Spondyloarthritis -- The BACK-OFF JSpA Study

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Does Personalized Risk Information Help Patients and Doctors Make Informed Decisions about Colorectal Cancer Screening?

Indiana University
| Indiana
Peter H. Schwartz, MD, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Admit Children to Hospitals

Dartmouth-Hitchcock Clinic^
| New Hampshire
JoAnna Leyenaar, MD, MPH, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Acupuncture and Massage to Treat Pain in Patients with Advanced Cancer -- The IMPACT Study

Memorial Sloan Kettering
| New York
Jun J. Mao, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Supporting Shared Decision Making between Clinicians and Older Adults about Colorectal Cancer Screening -- The PRIMED Study

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD, and Leigh Simmons, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Using Two Versus Three Antibiotics to Treat MAC Lung Infections

Oregon Health & Science University
| Oregon
Kevin Winthrop, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Strategies for Health Clinics to Increase HPV Vaccinations in Youth

UCLA School of Public Health
| California
Roshan Bastani, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Radiation Treatments for Localized Prostate Cancer - COMPPARE

University of Florida Board of Trustees
| Florida
Nancy Mendenhall, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Community Health Worker and Mobile Health Programs to Help Young Adults with Sickle Cell Disease Transition to Using Adult Healthcare Services -- The COMETS Study

The Childrens' Hospital of Philadelphia
| Pennsylvania
Tanisha Belton, DrPh, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Transitional Care for Teens and Young Adults with Sickle Cell Disease with and without Peer Mentoring

Atrium Health
| North Carolina
Payal Desai
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Provide Palliative Care to Older Adults with Serious Illness

New York University School of Medicine
| New York
Keith S. Goldfeld, DrPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

A New Statistical Method for Designing Stepped-Wedge Cluster Trials

University of Texas Southwestern Medical Center at Dallas
| Texas
Song Zhang, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

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