Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 19 of 19 results

Project Title
Project Status
Project Type

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Supporting Families' Treatment Decisions with Evidence on Treatment of Urea Cycle Disorders

Children's National Health System
| District of Columbia
Nicholas Ah Mew, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Dissemination Project (Limited Competition D&I PFA)

Comparing Telehealth and In-Person Care for Patients with Chronic Conditions

Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Manage Diabetes among African-American Women in the Southeast

Meharry Medical College
| Tennessee
Stephania Miller-Hughes, PhD, MS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Promote Healthy Weight Gain and Prevent Obesity in Early Childhood

Vanderbilt University Medical Center
| Tennessee
William J. Heerman, MD, MPH^
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Treat Childhood Obesity -- The TEAM UP Study

Washington University
| Missouri
Denise Wilfley, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

New Methods to Improve Data Accuracy in Studies Using Electronic Health Record Data

Vanderbilt University Medical Center
| Tennessee
Bryan E. Shepherd, PhD; Pamela A. Shaw, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Do Medicaid Health Homes Improve the Health of Adults with Diabetes?

Icahn School of Medicine at Mount Sinai
| New York
Victoria Mayer, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Assessing the Effects of Intensive Behavioral Therapy on Weight Loss among Patients with or at Risk for Type 2 Diabetes

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Jennifer Kraschnewski, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study

Kaiser Permanente Washington Health Research Institute^
| Washington
David Arterburn, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Treat Low Back Pain and Prevent Chronic Pain and Disability -- The TARGET Trial

University of Pittsburgh
| Pennsylvania
Anthony Delitto, PhD, PT, FAPTA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

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