Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 40 results

Project Title
Project Status
Project Type

Improving Instrumental Variables Methods for Non-Randomized Studies

The Trustees of The University of Pennsylvania
| Pennsylvania
Luke Keele, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

PEDSnet: Advancing Pediatric Patient-Centered Outcomes Research in PCORnet

The Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

INSIGHT Clinical Research Network

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

OneFlorida+ Partner Engagement Network

University of Florida
| Florida
Elizabeth Shenkman, PhD
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Accelerating Data Value Across a National Community Health Center Network (ADVANCE) Clinical Research Network (CRN)

Oregon Community Health Information Network, Inc. (OCHIN)
| Oregon
Erika Cottrell, PhD, MPP
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Greater Plains Collaborative Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research: PCORnet, The National Patient-Centered Clinical Research Network: Phase 3

University of Missouri
| Missouri
Lemuel Waitman, PhD, MS, BS
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

The Stakeholders, Technology and Researchers (STAR) Clinical Research Network: Phase 3

Vanderbilt University Medical Center
| Tennessee
Russell Rothman, MD, MPP
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

PaTH to Health: PCORnet Clinical Research Network

University of Pittsburgh School of Medicine
| Pennsylvania
Kathleen McTigue, MD, MPH, MS
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

REACHnet 3.0: Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research

Louisiana Public Health Institute
| Louisiana
Thomas Carton, PhD, MS, BS
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Developing Methods to Identify and Communicate Benefits and Harms of Digital Health Research Studies

The Regents of the University of California, San Diego
| California
Camille Nebeker, EdD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Developing a New Method to Combine Different Types of Trial Data in Meta-Analyses

The Regents of the University of California, San Francisco
| California
Mi-Ok Kim, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Helping Researchers Assess How Well Data Reflect Clinical Context

Children's Hospital of Philadelphia
| Pennsylvania
Charles Bailey, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Developing Methods to Combine Data Sources for Health Research

Johns Hopkins Bloomberg School of Public Health
| Maryland
Elizabeth Stuart, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing New Methods for Assessing Heterogeneity of Treatment Effect in Cluster Randomized Trials

Yale School of Public Health
| Connecticut
Fan Li, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods to Combine and Analyze Data from PRPP-SMART Studies

University of Michigan
| Michigan
Kelley Kidwell, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing How Well Different Diabetes Medicines Reduce the Risk of Heart Disease

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Romain Neugebauer, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients Who Are at Risk for Heart Disease

Mayo Clinic
| Minnesota
Rozalina McCoy, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods to Help Identify Patients with Rare Diseases in Electronic Health Records

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Daniel Herman, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Creating Recommendations on Types of Data to Present in Patient-Reported Outcome Measure Development Studies

University of Michigan
| Michigan
Joel Joseph Gagnier, PhD ND, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Different Data Sets to Test How Well Clinical Prediction Models Work to Predict Patients' Risk of Heart Disease

Tufts Medical Center
| Massachusetts
David M. Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Improving Methods for Discrete Choice Experiments to Measure Patient Preferences

North Carolina State University
| North Carolina
Alan R. Ellis, PhD, MSW
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing a New Method for Combining Data from Multiple Studies

Johns Hopkins University
| Maryland
Nilanjan Chatterjee, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing and Testing Software for Linking Patient Data from Multiple Sources

Texas A&M University Health Science Center
| Texas
Hye-Chung Kum, PhD, MSW, MS, FAMIA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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