Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 27 results

Project Title
Project Status
Project Type
Project Status:
Awarded; Contract pending
Project Type:
Research

Learning to Predict Disease Trajectories

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Mei-Sing Ong, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Identification of Temporal Data Patterns Predictive of Adverse Outcomes in Patients with Diabetes

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Fast and Robust Weighting Methods for Targeted Comparative Effectiveness Research

President and Fellows of Harvard College
| Massachusetts
Jose Zubizarreta, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Transportability of Machine Learning-Enabled Confounding Control Methods Across EHR Databases

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Richard Wyss, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving Methods for Benchmarking and Joint Analysis for Observational Studies

President and Fellows of Harvard College
| Massachusetts
Issa Dahabreh, MD, ScD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Toward a New Generation of Matching Methods for Comparative Effectiveness Research

Harvard Medical School
| Massachusetts
Jose R. Zubizarreta, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Developing New Methods for Comparing Treatments in Case-Control Studies

Harvard T.H. Chan School of Public Health
| Massachusetts
Goodarz Danaei, MD, MS, DSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing Two Patient Surveys for Diagnosing Rare Genetic Conditions

Boston Children's Hospital
| Massachusetts
Ingrid A. Holm, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Creating a New Process to Include Medical Device Information in Insurance Claims

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Joel S. Weissman, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Linking Randomized Clinical Trials and ClaiTRD Data for Enhancing Randomized and Non-Randomized Patient-Centered Outcomes Evidence Generation

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Mehdi Najafzadeh, PhD, MA, TRD
Project Status:
Awarded; Contract not executed
Project Type:
Research
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Improving Methods for Analyzing Data from Case-Only Studies

President & Fellows of Harvard College
| Massachusetts
Murray A. Mittleman, MD, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing Guidance for the Analysis of Randomized Controlled Trials in Real-World Settings

Harvard University School of Public Health
| Massachusetts
Miguel Hernán, MD, DrPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods to Apply Results from Randomized Trials to Patients in Clinical Practice

Harvard TH Chan School of Public Health
| Massachusetts
Issa J. Dahabreh, MD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing Recommendations for Oversight of Patient-Centered Outcomes Research -- The PCOROS Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Joel S. Weissman, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Statistical Methods to Preserve Patient Privacy When Sharing and Analyzing Data

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Darren Toh, ScD, BPHAR, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Statistical Models That Predict if Patients Will Take a New Medicine as Directed

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Joshua J. Gagne, TRD, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing a Survey with Patient and Caregiver Input that Measures the Quality of Care Transitions from Hospital to Home

University of Massachusetts Medical School
| Massachusetts
Catarina Kiefe, MD, PhD^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods for Improving Confounding Control in Comparative Effectiveness Research Using Electronic Healthcare Databases

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Sebastian Schneeweiss, MD, MS, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Determining the Best Methods for Using Patient Registry Data in Clinical Research

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Daniel H. Solomon, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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