Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

Keyword Search

Refine Results:

Funding Type
Expand/Collapse Facets
Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
Year Completed
Reset Filters
Download Results

Displaying 1 - 24 of 24 results

Project Title
Project Status
Project Type

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

University of Pennsylvania
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Screen People for Anxiety, Substance Use Disorders, and Intimate Partner Violence before and after Giving Birth -- The LTWP Study

Medical University of South Carolina
| South Carolina
Constance Guille, MD, MSCR
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Treatment for Opioid Use Disorder before and during the COVID-19 Pandemic

Boston VA Research Institute, Inc.
| Massachusetts
Nicholas Livingston, PhD and Risa Weisberg, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparative Effectiveness of Single-Site and Scattered-Site Permanent Supportive Housing on Patient-Centered and COVID-19 Related Outcomes for People Experiencing Homelessness

University of Southern California
| California
Benjamin Henwood, PhD, MA, MSW
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Three Ways to Start Taking Medicine for Opioid Use Disorder

University of Colorado Anschutz Medical Campus
| Colorado
Linda Zittleman, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Pregnant Women with Prenatal Care and Treatment for Opioid Use Disorder

Yale University School of Medicine
| Connecticut
Ariadna Forray
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research

Remote Cognitive Behavior Therapy for Major Depression in Primary Care

University of South Florida
| Florida
Robert Bossarte, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Depression Prevention Programs for Teens -- The Path 2 Purpose Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Standard Approach to Match Patients with Addiction to Treatment Based on Their Needs -- The PCAST Study

RTI International
| North Carolina
Tami L. Mark, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Cognitive Behavioral Therapy with Peer-Led Support Groups for Patients with Chronic Pain Who Want to Reduce Opioid Use -- The EMPOWER Study

Stanford University School of Medicine
| California
Beth Darnall, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Testing One State's Effort to Prevent Unsafe Treatments for Patients with Back Pain -- Back on Track

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| Washington
Lynn DeBar, PhD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Three Ways to Help Patients Manage Multiple Chronic Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Dan Swayze
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Programs to Treat Opioid Use Disorder in Primary Care and Substance Use Clinics

Public Health Management Corporation^
| Pennsylvania
David R. Gastfriend, MD
Project Status:
Terminated
Project Type:
Research
Has Results

Patient-Centered Hepatitis C Virus Care for People Who Inject Drugs -- The HERO Study

Clemson University^
| South Carolina
Alain Litwin, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Examining Effects of State Policies to Monitor Mental Health Medicines for Children in Foster Care

Rutgers University–New Brunswick
| New Jersey
Stephen Crystal, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Effect of High-Deductible Health Plans on Healthcare Use and Out-of-Pocket Costs for People with Bipolar Disorder

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
James Franklin Wharam, MB, BCh, BAO, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Clinic-Based Program to Reduce Risky Behaviors among Teens

Seattle Children's Hospital
| Washington
Carolyn McCarty, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Assessing Support for Medicine Decision Making for Youth with ADHD Who Receive Therapy

CASAColumbia
| New York
Aaron Hogue, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Effect of Integrating Mental and Physical Health on Patients' Experiences of Care

Providence Health & Services
| Oregon
Bill Wright, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Programs to Support Patients with Substance Use Disorders after They Leave the Hospital

Public Health Management Corporation
| Pennsylvania
Adam Brooks, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Impact of Patient Navigators on Health Education and Quality of Life in Formerly Incarcerated Patients

St. Luke's Hospital of Columbia University
| New York
Georgina Osorio, MD, MPH
Project Status:
Terminated
Project Type:
Research

What's Happening at PCORI?

The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.

Subscribe to PCORI Emails
Hand pointing to email icon