Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 22 of 22 results

Project Title
Project Status
Project Type
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Medicines for Adults with Myasthenia Gravis -- The PROMISE-MG Study

Duke University
| North Carolina
Donald B. Sanders, MD, and Pushpa Narayanaswami, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Identify Sleep Apnea in People with Traumatic Brain Injury during Inpatient Rehabilitation

Tampa VA Research and Education Foundation
| Florida
Risa Nakase-Richardson, PhD, FACRM, FNAN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study

Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study

Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Physical Therapy Schedules for Children with Cerebral Palsy -- The ACHIEVE Study

The Ohio State University
| Ohio
Jill C. Heathcock, MPT, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Looking at the Effect of Treatment Duration for Newborn Infants Who Have Seizures

University of Michigan
| Michigan
Renée A. Shellhaas, MD, MS & Hannah C. Glass, MDCM, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Surgery with and without Duraplasty for Youth with Chiari Malformation Type I and Syringomyelia

Washington University School of Medicine
| Missouri
David Limbrick, MD, MS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity

Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Stopping or Continuing Use of Disease Modifying Therapies in Older Adults with Multiple Sclerosis -- The DISCOMS Trial

University of Colorado Denver
| Colorado
John R. Corboy, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Entry Sites for Cerebrospinal Fluid Shunts in Children with Hydrocephalus

Baylor College of Medicine
| Texas
William Whitehead, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Automated Tracking of Symptoms and Treatment Side Effects to Help Patients Starting New Medicines for Diabetes-Related Nerve Pain

Kaiser Foundation Research Institute
| California
Alyce Sophia Adams, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Reducing Burden on Hispanic Caregivers of Relatives with Dementia -- The Northern Manhattan Hispanic Caregiver Intervention Effectiveness Study (NHiCE)

Columbia University Health Sciences
| New York
Jose Alejandro Luchsinger, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding the Development of Children with Cerebral Palsy and How Therapy May Affect Patient-Centered Outcomes

University of Washington
| Washington
Sarah Westcott McCoy, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Five Activities to Improve Quality of Life for Patients with Mild Cognitive Impairment

University of Florida^
| Florida
Glenn E. Smith, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Plasma Exchange Help Improve Physical Function in Children with Transverse Myelitis? -- The CAPTURE Study

University of Texas Southwestern Medical Center
| Texas
Benjamin M. Greenberg, MD, MHS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Four Medicines to Treat Pain from Cryptogenic Sensory Polyneuropathy (CSPN) -- The PAIN-CONTRoLS Study

University of Kansas Medical Center
| Kansas
Richard J. Barohn, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Coordinated-Care Management Approach Improve Care and Health for Patients with a Sleep Disorder? -- SMART DOCS

Stanford University School of Medicine
| California
Clete Kushida, MD, MS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can Using Patient Reports of Low Back Pain Help to Better Direct Patients to Treatments?

Kaiser Foundation Health Plan of Washington^
| Washington
Dan Cherkin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Nonsurgical Treatments for Lumbar Spinal Stenosis in Reducing Pain and Increasing Walking Ability

University of Pittsburgh
| Pennsylvania
Michael J. Schneider, DC, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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