Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 22 of 22 results

Project Title
Project Status
Project Type

A Randomized Controlled Trial to Evaluate a Trauma-Informed Partner Violence Intervention Program

Trustees of Boston University, BUMC
| Massachusetts
Casey Taft, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Improving In-Hospital Sleep Hygiene to Prevent and Curtail Delirium Among Older Adults

The Methodist Hospital Research Institute
| Texas
Farhaan Vahidy, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

The SCOPE Trial: Sleep, Cognition, and Pain Bundle Versus Enhanced Recovery After Surgery-Cardiac for Postoperative Delirium

Beth Israel Deaconess Medical Center
| Massachusetts
Balachundhar Subramaniam, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Patient-Level Artificial Intelligence to Derive Longitudinal Phenotypes for Comparative Clinical Effectiveness Research

Dana-Farber Cancer Institute
| Massachusetts
Kenneth Kehl, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Pathways to Perinatal Mental Health Equity (Pathways)

UMass Chan Medical School
| Massachusetts
Nancy Byatt, B.A., D.O., MBA, M.S.
Project Status:
Awarded; Contract pending
Project Type:
Research

Preoperative Fasting Versus Not Fasting in Critically Ill Patients

Massachusetts General Hospital/Harvard Medical School
| Massachusetts
Alexander Nagrebetsky, M.D., M.S.
Project Status:
Awarded; Contract pending
Project Type:
Research

Promoting Shared Decision Making About Colorectal Cancer Testing in Older Adults

The General Hospital Coporation d/b/a Massachusetts General Hospital
| Massachusetts
Karen Sepucha, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Effectiveness of Brief Intervention in Primary Care for Diverse Young People

RAND Corporation
| Massachusetts
Elizabeth D'Amico, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of Lifestyle Interventions for Older Cancer Survivors and Their Caregivers

Dana-Farber Cancer Institute
| Massachusetts
Christina Dieli-Conwright, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Measurement Matters: Refining and Validating a Patient-Centered Outcomes Research Engagement Measure

University of Massachusetts Boston
| Massachusetts
Marc Cohen, Ph.D., M.A.
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Hospital Elder Life Program (HELP) vs. Family-Augmented HELP (FAM-HELP) for Prevention of Delirium

Hebrew Rehabilitation Center
| Massachusetts
Sharon Inouye, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Testing Scalable, Broad-Reach School-Based Brief Interventions for Alcohol Use

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Randi Schuster, PhD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Effectiveness of Interventions to Improve Resiliency and Burnout in Behavioral Health Residential Staff

Massachusetts General Hospital
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Pacing Treatments for Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Mild Hypoxic Ischemic Encephalopathy in Infants -- The COOLPRIME Study

UT Southwestern Medical Center
| Texas
Lina Chalak, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Effectiveness of a Multimodal Intervention for Transitions of Care after Lower Limb Fracture

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Patricia Dykes, PhD, RN, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparing Behavior Therapy and Yoga for Treating Depression among Adults

Massachusetts General Hospital
| Massachusetts
Louisa Sylvia, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Follow Up after a Child Goes Home from the Hospital -- The FAAN-C Trial

University of Utah
| Utah
Eric Coon, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Programs to Decrease HIV Risk among African-Born Black Women

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Bisola Ojikutu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

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