Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 126 - 150 of 177 results

Project Title
Project Status
Project Type
Has Results

Comparing Two Types of Anesthesia for Hip Fracture Surgery -- The REGAIN Trial

University of Pennsylvania
| Pennsylvania
Mark D. Neuman, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Medicines to Treat Crohn’s Disease in Children and Adolescents -- The COMBINE Trial

The University of North Carolina at Chapel Hill
| North Carolina
Michael D. Kappelman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Improve Prescribing of Colony-Stimulating Factor in Cancer Treatment -- The TrACER Study

Fred Hutchinson Cancer Research Center
| Washington
Scott D. Ramsey, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Restrictive Diets for Treating Eosinophilic Esophagitis in Children

Cincinnati Children's Hospital Medical Center
| Ohio
Marc Rothenberg, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Statistical Methods to Preserve Patient Privacy When Sharing and Analyzing Data

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Darren Toh, ScD, BPHAR, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods for Comparing Treatments Using Different Ways of Grouping Patients

University of California, San Francisco^
| California
Mi-Ok Kim, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Creating and Testing Methods to Estimate Treatment Effect in Observational Studies with Three or More Treatments

Brown University
| Rhode Island
Roee Gutman, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Way to Keep Staph Infections from Recurring

Clinical Directors Network, Inc.
| New York
Jonathan N. Tobin, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways of Treating Rheumatoid Arthritis When Patients Are in Remission -- The STARA Study

Georgetown University
| District of Columbia
Florina Constantinescu, MD, PhD^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Monitoring Oxygen Levels of Premature Babies at Home and in the Clinic -- The RHO Trial

University of Massachusetts Medical School^
| Massachusetts
Lawrence Rhein, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Assessing Support for Medicine Decision Making for Youth with ADHD Who Receive Therapy

CASAColumbia
| New York
Aaron Hogue, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help African Americans Who Are Non-Daily Smokers Quit Smoking

University of Kansas Medical Center Research Institute, Inc.
| Kansas
Nikki Nollen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Medicine Combinations Used to Treat Schizophrenia

Columbia University Health Sciences
| New York
Thomas S. Stroup, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Depression among Patients with Kidney Failure Receiving Hemodialysis -- The ASCEND Study

University of Washington
| Washington
Rajnish Mehrotra, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Graphic Novels when Choosing Treatment for Alcohol Use Disorder

Public Health Management Corporation^
| Pennsylvania
Adam Brooks, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Statistical Models That Predict if Patients Will Take a New Medicine as Directed

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Joshua J. Gagne, TRD, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating a Program to Lower Prescription Opioid Doses for Patients with Chronic Pain

Kaiser Foundation Health Plan of Washington^
| Washington
Michael Von Korff, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods for Improving Confounding Control in Comparative Effectiveness Research Using Electronic Healthcare Databases

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Sebastian Schneeweiss, MD, MS, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing Software for Using Bayesian Regression to Evaluate Heterogeneity of Treatment Effects in Data from Randomized Controlled Trials

Johns Hopkins University
| Maryland
Ravi Varadhan, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Determining the Best Methods for Using Patient Registry Data in Clinical Research

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Daniel H. Solomon, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Smartphone App Help Patients with Cancer Take Oral Chemotherapy as Planned?

Massachusetts General Hospital
| Massachusetts
Joseph A. Greer, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Broad- and Narrow-Spectrum Antibiotics for Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Examining Health Outcomes for People Who Are Transgender

Emory University
| Georgia
Michael Goodman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help People with COPD Stop Smoking

University of Kansas Medical Center
| Kansas
Edward Ellerbeck, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Treatment and Patient Characteristics Affecting the Health Status of Patients with Peripheral Arterial Disease -- The PORTRAIT Study

Saint Luke's Hospital
| Missouri
Kim G. E. Smolderen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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