Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 54 results

Project Title
Project Status
Project Type

Comparing Two Online Programs for Treating Chronic Pain -- The PROGRESS Study

Stanford University
| California
Beth Darnall, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Types of Medicine for Pain after Surgery -- The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Reduce Flare-Ups among People with Inflammatory Bowel Disease -- The QUOTIENT Study

University of California San Diego
| California
Siddharth Singh, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Testing a Program to Improve Quality of Life among Latina Breast Cancer Survivors and Their Partners

University of South Florida
| Florida
Dinorah Martinez Tyson, PhD, MPH, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

The University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Improving Methods for Identifying Social, Behavioral, and Clinical Factors in Doctors' Notes in Electronic Health Records

University of Florida
| Florida
Yonghui Wu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Improve Asthma Symptoms in Children: Reducing Cockroaches vs. Reducing Multiple Triggers

Tulane School of Public Health and Tropical Medicine
| Louisiana
Felicia A. Rabito, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Acupuncture and Massage to Treat Pain in Patients with Advanced Cancer -- The IMPACT Study

Memorial Sloan Kettering
| New York
Jun J. Mao, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

What Is the Effect of Adding a Health Coach to Patient-Centered Medical Homes for Managing Multiple Chronic Conditions?

Clinical Directors Network
| New York
Jonathan Tobin, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Expanding Use of a Decision Aid to Help People with Lupus Nephritis Make Decisions about Treatment

University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Home- Versus Clinic-Based Phototherapy for the Treatment of Psoriasis -- The LITE Study

University of Pennsylvania
| Pennsylvania
Joel Mitchell Gelfand, MD, MS
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Ways to Provide Palliative Care to Older Adults with Serious Illness

New York University School of Medicine
| New York
Keith S. Goldfeld, DrPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Two Medicines for Adults with Myasthenia Gravis -- The PROMISE-MG Study

Duke University
| North Carolina
Donald B. Sanders, MD, and Pushpa Narayanaswami, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing a New Method for Combining Data from Multiple Studies

Johns Hopkins University
| Maryland
Nilanjan Chatterjee, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients Manage Symptoms at Home after Cancer Surgery -- The ACCESS Study

Memorial Sloan Kettering Cancer Center
| New York
Brett Simon, MD, PhD, and Andrea Pusic, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping Women with Breast Cancer Choose between Surgical Treatment Options

Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, MSc^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Breast Cancer Screening and Diagnostic Tests among Women with Different Breast Densities -- The BCSC-ADVANCE Study

University of California, Davis
| California
Diana L. Miglioretti, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating a Telehealth Program for Ostomy Self-Care among Cancer Survivors

The Trustees of the University of Pennsylvania^
| Pennsylvania
Robert S. Krouse, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment for Ductal Carcinoma In Situ (DCIS) with or without Sentinel Lymph Node Biopsy

Yale University
| Connecticut
Shiyi Wang, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Research Networks to Compare Medicines for Autoimmune and Inflammatory Diseases -- The Comparative Health Outcomes in Immune-mediated diseases CollaborativE (CHOICE) Study

University of Alabama at Birmingham
| Alabama
Jeffrey R. Curtis, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatment Options for Women with Low-Risk Ductal Carcinoma In Situ (DCIS) -- The COMET Study

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Shelley Hwang, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

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