Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 26 results

Project Title
Project Status
Project Type

PEDSnet: Advancing Pediatric Patient-Centered Outcomes Research in PCORnet

The Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

INSIGHT Clinical Research Network

Weill Cornell Medicine
| New York
Rainu Kaushal, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

OneFlorida+ Partner Engagement Network

University of Florida
| Florida
Elizabeth Shenkman, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Accelerating Data Value Across a National Community Health Center Network (ADVANCE) Clinical Research Network (CRN)

Oregon Community Health Information Network, Inc. (OCHIN)
| Oregon
Erika Cottrell, PhD, MPP
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Greater Plains Collaborative Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research: PCORnet, The National Patient-Centered Clinical Research Network: Phase 3

University of Missouri
| Missouri
Lemuel Waitman, PhD, MS, BS
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

The Stakeholders, Technology and Researchers (STAR) Clinical Research Network: Phase 3

Vanderbilt University Medical Center
| Tennessee
Russell Rothman, MD, MPP
Project Status:
Awarded; In progress
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

PaTH to Health: PCORnet Clinical Research Network

University of Pittsburgh School of Medicine
| Pennsylvania
Kathleen McTigue, MD, MPH, MS
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

REACHnet 3.0: Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research

Louisiana Public Health Institute
| Louisiana
Thomas Carton, PhD, MS, BS
Project Status:
Awarded; Contract pending
Project Type:
Research Infrastructure, PCORnet®: Clinical Research Network (Phase 3)

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Treatment for Opioid Use Disorder before and during the COVID-19 Pandemic

Boston VA Research Institute, Inc.
| Massachusetts
Nicholas Livingston, PhD and Risa Weisberg, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Telehealth and In-Person Care for Patients with Chronic Conditions

Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Programs to Train Staff to Reduce the Spread of COVID-19 in Nursing Homes

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Jennifer L. Kraschnewski, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing How State and Local COVID-19 Policies Affect Patient-Reported Outcomes

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Protecting the Well-Being of Healthcare Workers during the COVID-19 Pandemic -- The COVER-HCW Project

RAND Corporation
| California
Lisa S. Meredith, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparative Effectiveness of Single-Site and Scattered-Site Permanent Supportive Housing on Patient-Centered and COVID-19 Related Outcomes for People Experiencing Homelessness

University of Southern California
| California
Benjamin Henwood, PhD, MA, MSW
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Testing the Effectiveness of a Text-Message-Based Home Monitoring Program and Oxygen Monitoring for Patients with COVID-19 -- The COVID Watch Study

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Kit Delgado, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Deliver Remote Mental Health Support during the COVID-19 Pandemic

The Research Foundation For The State University of New York
| New York
Yu-Ping Chang, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing a Multiple Sclerosis Fatigue Management Course Delivered via Teleconference, Internet, or in Person

Case Western Reserve University
| Ohio
Matthew A. Plow, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Home and Facility-Based Exercise to Improve Mobility in People with Multiple Sclerosis -- STEP for MS

Shepherd Center
| Georgia
Deborah A. Backus, PhD, PT
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Examining Whether Early Aggressive Therapy Can Prevent or Delay Disability in People with Multiple Sclerosis: the TREAT-MS Study

Johns Hopkins University
| Maryland
Ellen M. Mowry, MD, MCR
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Approaches to Treat Relapsing-Remitting Multiple Sclerosis -- the DELIVER-MS Study

Cleveland Clinic Foundation
| Ohio
Daniel Ontaneda, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Oral Medicines to Improve Patient Experiences with Relapsing-Remitting Multiple Sclerosis -- PRAG-MS

Fondazione IRCCS Istituto Neurologico "Carlo Besta" (Italy)
| N/A
Renato Mantegazza, MD^
Project Status:
Terminated
Project Type:
Research

Comparing Clinic- and Home-Based Exercise Programs to Help Adults with Multiple Sclerosis -- The TEAMS Study

University of Alabama at Birmingham
| Alabama
James Rimmer, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study

Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

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