Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 113 results

Project Title
Project Status
Project Type
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Acupuncture and Massage to Treat Pain in Patients with Advanced Cancer -- The IMPACT Study

Memorial Sloan Kettering
| New York
Jun J. Mao, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Supporting Shared Decision Making between Clinicians and Older Adults about Colorectal Cancer Screening -- The PRIMED Study

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD, and Leigh Simmons, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Medicines to Treat Ulcerative Colitis and Crohn's Disease When Anti-TNF Medicines Don't Work

The University of North Carolina at Chapel Hill^
| North Carolina
Michael D. Kappelman, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Meditation versus Medicine for Patients with Anxiety Disorders

Georgetown University Medical Center
| District of Columbia
Elizabeth Hoge, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Treat Insomnia among Black Women

Boston University
| Massachusetts
Lynn Rosenberg, ScD, MS, and Eric Zhou, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Stroke Prevention in Atrial Fibrillation Patients: A Systematic Review Update

Memorandum of Understanding with Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Completed
Project Type:
Research
Has Results

Evaluating Hormone Treatments for Women at Increased Risk for Preterm Birth -- The EPPPIC Study

University of York (United Kingdom)
| N/A
Lesley Stewart, PhD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Antiseptic Skin Solutions to Prevent Infection in Patients Having Surgery to Treat Fractures -- The PREPARE Study

University of Maryland, Baltimore
| Maryland
Gerard P. Slobogean, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs to Maintain Weight Loss among Black Women with Obesity

University of Florida
| Florida
Carolyn M. Tucker, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Treat Depression among Pregnant Women and New Mothers with Low Incomes

Boston Medical Center
| Massachusetts
Michael Silverstein, MD, MPH; Caroline J Kistin, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs for Weight Loss among Marshallese Adults Living in the United States

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, PhD, MS, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients and Doctors Talk about Chronic Pain Treatments -- Voices in Pain Care

Cedars-Sinai Medical Center
| California
Brennan Spiegel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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