Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 45 results

Project Title
Project Status
Project Type

Support for Transgender and Nonbinary Individuals Seeking Vaginoplasty (STRIVE) Study

Oregon Health & Science University
| Oregon
Geolani Dy, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

The Missing Pieces Trial: A Multi-Site Pragmatic Comparative Effectiveness Trial of Interventions to Support Parents After Their Child's Unexpected or Traumatic Death

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Kelly Michelson, M.D., MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Support Parents in Breastfeeding -- The FEEDS Study

NorthShore University HealthSystem
| Illinois
Ann Borders, MD, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Does a Black Midwifery Program Improve Maternity Care for Black Women?

The Board of Trustees of the University of Illinois
| Illinois
Kylea Liese, PhD, CNM
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Improve Mental Health among Youth with Disabilities -- The BEST Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Treatments for Children with Lennox-Gastaut Syndrome

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Sandi Lam, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Care in the CCP Program versus Care in the C4P Program versus Care in Traditional Care Coordinator Program

The University of Chicago
| Illinois
David O. Meltzer, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Anxiety Disorders among Children and Adolescents

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
John T. Walkup, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Obtain Hearing Aids for People with Age-Related Hearing Loss

Northwestern University
| Illinois
Sumitrajit Dhar, PhD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Depression Prevention Programs for Teens -- The Path 2 Purpose Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Using Two Versus Three Antibiotics to Treat MAC Lung Infections

Oregon Health & Science University
| Oregon
Kevin Winthrop, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Two Ways to Provide Advance Care Planning in Primary Care Clinics to Patients with a Serious Illness

Oregon Health & Science University
| Oregon
Annette M. Totten, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Identifying and Treating Childhood Hearing Loss in Rural Alaska -- The Hearing Norton Sound Study

Norton Sound Health Corporation
| Alaska
Samantha Kleindienst Robler, AuD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Electronic Symptom Monitoring versus Usual Care in Improving Survival among Patients with Metastatic Cancer -- The PRO-TECT Trial

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Ethan Basch, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Measuring the Effects of Social Risks on Patient Health Outcomes -- A PCORnet® Study

Oregon Community Health Information Network, Inc. (OCHIN)
| Oregon
Abigail Sears, MBA, MHA and Erika Cottrell, PhD, MPP^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Does a Web-Based Decision Aid Help Patients and Their Doctors Decide How to Treat Hip and Knee Arthritis?

Northwestern University^
| Illinois
Patricia D. Franklin, MD, MBA, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Testing the Effectiveness of Adding Group Therapy to Home Visiting Services on Reducing Postpartum Depression in Women with Low Incomes

Northwestern University
| Illinois
Darius Tandon, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Medicines to Prevent Chronic Obstructive Pulmonary Disease Episodes -- The RELIANCE Study

University of Illinois at Chicago
| Illinois
Jerry A. Krishnan, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatment Options for Women with Low-Risk Ductal Carcinoma In Situ (DCIS) -- The COMET Study

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Shelley Hwang, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Treatment with Long-Term Steroids or Long-Term Antibiotics to Prevent Lung Infections in Patients with Bronchiectasis

Oregon Health & Science University
| Oregon
Kevin Winthrop, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Types of Blood Thinners to Prevent Blood Clots in Patients with Cancer -- The CANVAS Trial

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Deborah Schrag, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Adding a Teachable Moment Approach to a Team-Based Primary Care Ask-Advise-Connect Approach for Tobacco Cessation

Oregon Health & Science University^
| Oregon
Susan (Sue) Flocke, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of How Often Men Have PSA Testing in the First Year after Prostate Cancer Treatment

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Ronald C. Chen, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Accuracy of Health Record Data and Self-Reported Data

Oregon Health & Science University
| Oregon
Anita Walden, MS^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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