Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 71 results

Project Title
Project Status
Project Type

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

University of Pennsylvania
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Four Ways to Reduce Pregnancy Complications among Black Mothers -- The ACURE4Moms Study

University of North Carolina at Chapel Hill School of Medicine
| North Carolina
Jennifer Tang, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Provide Maternal Mental Health Treatment to Women Who Are Black or of African Descent Living in Washington, DC

Children's Research Institute
| District of Columbia
Catherine Limperopoulos, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Testing Two Ways to Increase Receipt of Early Kidney Transplants among Patients with Kidney Failure

Duke University
| North Carolina
Leigh Ebony Boulware, MD, MPH, FACP
Project Status:
In progress; Recruiting
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Treatment for Opioid Use Disorder before and during the COVID-19 Pandemic

Boston VA Research Institute, Inc.
| Massachusetts
Nicholas Livingston, PhD and Risa Weisberg, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing How State and Local COVID-19 Policies Affect Patient-Reported Outcomes

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Help Older Adults Living in Low-Income Housing Maintain Their Health and Independence -- The EPIC Study

Cedars-Sinai
| California
Harriet Aronow, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Provide Follow-Up Care to Patients with Heart Failure after Hospital Discharge -- MIGHTY-Heart

The Trustees of Columbia University in the City of New York
| New York
Ruth Masterson Creber, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Improve Pre-Exposure Prophylaxis (PrEP) Use for HIV Prevention

Public Health Foundation Enterprises, Inc.
| California
Albert Liu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Two Ways to Provide Enhanced Prenatal Care to Improve Health in Mothers and Babies -- The EMBRACE Study

University of California, San Francisco
| California
Miriam Kuppermann, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Increase HPV Testing for Cervical Cancer Screening

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Chun Chao, PhD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Help African-American and Latino Patients with HIV to Receive and Retain Care

Johns Hopkins School of Medicine
| Maryland
Kathleen Page, MD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Two Programs to Reduce Unsafe Opioid Prescribing and Improve Outcomes among People Who Are Injured at Work -- The WOW Study

University of Washington
| Washington
Gary Franklin, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Connecting Low-Income Tobacco Users with a Telephone Quitline to Help Them Quit

University of Utah
| Utah
David Wetter, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Ways to Coordinate Care for Patients after Trauma

University of Washington
| Washington
Douglas Zatzick, MD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Testing a Standard Approach to Match Patients with Addiction to Treatment Based on Their Needs -- The PCAST Study

RTI International
| North Carolina
Tami L. Mark, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Strategies for Health Clinics to Increase HPV Vaccinations in Youth

UCLA School of Public Health
| California
Roshan Bastani, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Health-System-Based and Community-Based Dementia Care for Patients and Caregivers -- D-CARE: The Dementia Care Study

Regents of the University of California, Los Angeles
| California
David Reuben, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Testing One State's Effort to Prevent Unsafe Treatments for Patients with Back Pain -- Back on Track

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| Washington
Lynn DeBar, PhD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Provide Palliative Care to Older Adults with Serious Illness

New York University School of Medicine
| New York
Keith S. Goldfeld, DrPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Offer Palliative Care to Improve Quality of Life for Patients with End-Stage Liver Disease

Thomas Jefferson University
| Pennsylvania
Victor J. Navarro, MD, BS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Encourage and Improve End-of-Life Care Planning

Duke University
| North Carolina
Kimberly Johnson, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Approaches to Advance Care Planning for Patients with Advanced Illness

Regents of the University of California, Los Angeles
| California
Neil S. Wenger MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

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