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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 78 results

Project Title
Project Status
Project Type

Semantic Data Quality Standards for Multi-Center Clinical Research Studies and Networks

Children's Hospital of Philadelphia
| Pennsylvania
Charles Bailey, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Achieving Blood Pressure Goals after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

PRECIDENTD (PREvention of CardIovascular and DiabEtic kidNey disease in Type 2 Diabetes)

Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Monitor and Treat High Blood Pressure in Children with Chronic Kidney Disease -- The PRESERVE Study

Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Palliative Surgery versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Sandi Lam
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Utilizing PCORnet to Support Transition from Pediatric to Adult-Centered Care and Reduce Gaps in Recommended Care in Patients with Congenital Heart Disease

Louisiana Public Health Institute
| Louisiana
Thomas Carton, PhD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing the Effects of Different Treatment Approaches for Neuroendocrine Tumors on Patient-Reported Outcomes -- The NET-PRO Study

University of Iowa
| Iowa
Michael O'Rorke, PhD, BSc
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

BESTMED: Observational Evaluation of Second-Line Therapy Medications in Diabetes

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Development of Methods to Improve Identification of Patients with Rare or Complex Diseases

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Daniel Herman, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Biologic Abatement and Capturing Kids? Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA)

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Telehealth and In-Person Care for Patients with Chronic Conditions

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing How State and Local COVID-19 Policies Affect Patient-Reported Outcomes

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Manage Diabetes among African-American Women in the Southeast

Meharry Medical College
| Tennessee
Stephania Miller-Hughes, PhD, MS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Research Action for Health Network (REACHnet) Clinical Research Network

Louisiana Public Health Institute
| Louisiana
Thomas W. Carton, PhD, MS
Project Status:
Awarded; Contract not executed
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

OneFlorida Clinical Research Consortium Clinical Research Network

University of Florida - UFHealth
| Florida
Betsy Shenkman, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

Accelerating Data Value Across a National Community Health Center Network (ADVANCE) Clinical Research Network

OCHIN, Inc.
| Oregon
Jon Puro, MPA, MHA
Project Status:
In progress; Recruitment not applicable
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

Path Towards a Learning Health System (PaTH) Clinical Research Network

University of Pittsburgh
| Pennsylvania
Kathleen McTigue, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN) Clinical Research Network

Northwestern University–Center for Health Information Partnerships
| Illinois
Abel Kho, MD
Project Status:
Awarded; Contract not executed
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

INSIGHT Clinical Research Network

Weill Cornell Medicine
| New York
Rainu Kaushal, MD, MPH
Project Status:
Awarded; Contract not executed
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

PEDSnet Clinical Research Network

Children's Hospital of Philadelphia
| Pennsylvania
Christopher B. Forrest, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

The Greater Plains Collaborative (GPC CRN)

University of Missouri^
| Missouri
Russ Waitman, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

The Stakeholders, Technology, and Research Clinical Research Network (STAR CRN)

Vanderbilt University Medical Center
| Tennessee
Russell Rothman, MD, MPP
Project Status:
Awarded; Contract not executed
Project Type:
PCORnet: Clinical Research Network (CRN) 2020

Preventing COVID-19 Infections: Healthcare Worker Exposure Response and Outcomes (HERO) Registry and Hydroxychloroquine (HERO-HCQ) Trial Program

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Provide Follow-Up Care to Patients with Heart Failure after Hospital Discharge -- MIGHTY-Heart

Weill Cornell Medicine
| New York
Ruth Masterson Creber, PhD^
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

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