Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 84 results

Project Title
Project Status
Project Type

Comparing Two Pacing Treatments for Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

University of Pennsylvania
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Ways to Prevent Falls among Patients with Cirrhosis of the Liver

University of Michigan
| Michigan
Elliot Tapper, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Effectiveness of a Multimodal Intervention for Transitions of Care after Lower Limb Fracture

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Patricia Dykes, PhD, RN, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

Community-Based, Family-Centered, Trauma-Informed Approach to Timely Detection and Management of Early Postpartum Hypertension

Yale School of Public Health
| Connecticut
Rafael Perez-Escamilla, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Help People Quit Smoking

University of Florida
| Florida
Jesse Dallery, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Online Programs for Treating Chronic Pain -- The PROGRESS Study

Stanford University
| California
Beth Darnall, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Anesthesia for Surgery -- The THRIVE Trial

Regents of the University of Michigan
| Michigan
Sachin Kheterpal, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Improve Mental Health among Youth with Disabilities -- The BEST Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Provide Maternal Mental Health Treatment to Women Who Are Black or of African Descent Living in Washington, DC

Children's Research Institute
| District of Columbia
Catherine Limperopoulos, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Testing the Effectiveness of a Text-Message-Based Home Monitoring Program and Oxygen Monitoring for Patients with COVID-19 -- The COVID Watch Study

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Kit Delgado, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Deliver Remote Mental Health Support during the COVID-19 Pandemic

The Research Foundation For The State University of New York
| New York
Yu-Ping Chang, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Monitor Glucose among People with Type 2 Diabetes

HealthPartners Institute
| Minnesota
Richard Bergenstal, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Prevent Severe Hypoglycemia in Patients with Type 2 Diabetes

Kaiser Foundation Health Plan of Washington
| Washington
James Ralston, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Programs for Managing Hearing Loss among Older Adults in Assisted Living Facilities

University of Pittsburgh
| Pennsylvania
Catherine Palmer, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Obtain Hearing Aids for People with Age-Related Hearing Loss

Northwestern University
| Illinois
Sumitrajit Dhar, PhD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Manage Pain after High-Dose Chemotherapy

Memorial Sloan-Kettering Cancer Center
| New York
Gary Deng, MD, PhD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Acupuncture and Massage to Treat Pain in Patients with Advanced Cancer -- The IMPACT Study

Memorial Sloan Kettering
| New York
Jun J. Mao, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Three Ways to Help People with Opioid Use Disorder Take Medicines as Prescribed

Johns Hopkins University School of Medicine
| Maryland
Kenneth Silverman
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Two Ways to Provide Enhanced Prenatal Care to Improve Health in Mothers and Babies -- The EMBRACE Study

University of California, San Francisco
| California
Miriam Kuppermann, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

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