Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 6 of 6 results

Project Title
Project Status
Project Type

Using a Virtual Screening and Care Program to Increase Access to Treatment for Urinary Incontinence in Women

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Brian Mittman, PhD, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Improving Antibiotic Prescribing in Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)
Has Results

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Treatment Approaches for Older Adults with Treatment-Resistant Depression -- The OPTIMUM Study

Washington University School of Medicine
| Missouri
Eric J. Lenze, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing ECT and Ketamine in Adults with Treatment-Resistant Depression – The ELEKT-D Study

Cleveland Clinic Foundation
| Ohio
Amit Anand, MD^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Low-Dose versus High-Dose Aspirin to Prevent Problems from Heart Disease -- The ADAPTABLE Study -- A PCORnet® Study

Duke University
| North Carolina
William Schuyler Jones, MD*
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

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