Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 74 results

Project Title
Project Status
Project Type
Has Results

Protecting the Well-Being of Healthcare Workers during the COVID-19 Pandemic -- The COVER-HCW Project

RAND Corporation
| California
Lisa S. Meredith, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Ways to Provide Enhanced Prenatal Care to Improve Health in Mothers and Babies -- The EMBRACE Study

University of California, San Francisco
| California
Miriam Kuppermann, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Developing Methods to Improve the Use of Information about Medicine Refills in Analyses of Electronic Health Record Data

Kaiser Permanente Division of Research
| California
Romain Neugebauer, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results

Comparing Two Treatments for Depression among Patients with Advanced Heart Failure

Cedars-Sinai Health System
| California
Waguih William IsHak, MD, FAPA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Evaluating the Safety of Direct-Acting Antivirals for Treating Hepatitis C

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Elizabeth McGlynn, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Identifying Barriers to Telehealth Home-Based Palliative Care for Patients with Serious Illness -- The HomePal Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Huong Q. Nguyen, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Determining Whether Adding a Palliative Care Team Improves Quality of Life for Patients Who Have Had Upper Gastrointestinal Cancer Surgery -- The PERIOP-PC Study

Stanford University^
| California
Karl Lorenz, MD, MSHS^
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Support Communication between Patients and Their Primary Care Providers

University of California, San Diego^
| California
Ming Tai-Seale, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effects of Acupressure on Cancer Treatment Side Effects in Children and Youth -- The ACT-CC Study

University of California San Francisco
| California
E. Anne Lown, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients and Doctors Talk about Chronic Pain Treatments -- Voices in Pain Care

Cedars-Sinai Medical Center
| California
Brennan Spiegel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatments for Resistant Kawasaki Disease -- The KIDCARE Study

University of California San Diego
| California
Jane C. Burns, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Identifying Challenges to Using Home-Based Palliative Care for Patients with Serious Illness

University of Southern California
| California
Susan Enguidanos, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Treating Genital Herpes during Pregnancy Improve Birth Outcomes?

Kaiser Foundation Research Institute
| California
De-Kun Li, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs to Help Latino Men Lose Weight -- The HOMBRE Trial

Stanford University School of Medicine^
| California
Lisa G. Rosas, MPH, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment Strategies to Prevent Future Blood Clots among Patients Who Received at Least Three Months of Blood Thinners -- The ALTERNATIVE Study

University of California, San Francisco
| California
Margaret Fang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Breast Cancer Screening and Diagnostic Tests among Women with Different Breast Densities -- The BCSC-ADVANCE Study

University of California, Davis
| California
Diana L. Miglioretti, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Medications Added to a Serotonin Reuptake Inhibitor to Treat Patients with PTSD

University of California San Francisco
| California
Beth Cohen, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Improve Depression Symptoms among Adults who Identify as LGBTQ+ -- The RADD Study

University of California, Los Angeles
| California
Bowen Chung, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Using an iPad App in School Health Centers to Support Latina Teens Making Choices about Birth Control -- The Health-E You/Salud iTu Intervention

University of California San Francisco
| California
Kathleen P. Tebb, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Community and Patient Partnered Research Network (CPPRN)

University of California, Los Angeles
| California
Kenneth Wells, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
PCORnet®: Patient Powered Research Networks (PPRN) Phase II
Has Results

The Health eHeart Alliance

University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
PCORnet®: Patient Powered Research Networks (PPRN) Phase II
Has Results

PRIDEnet: A Participant-Powered Research Network of Sexual and Gender Minorities

University of California, San Francisco
| California
Mitchell R. Lunn, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
PCORnet®: Patient Powered Research Networks (PPRN) Phase II
Has Results

patient-centered SCAlable National Network for Effectiveness Research (pSCANNER)

University of California, San Diego
| California
Lucila Ohno-Machado, MD, MBA, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
PCORnet®: Clinical Data Research Networks (CDRN) Phase II

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