Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 98 results

Project Title
Project Status
Project Type

Preventing Suicidal Behavior with Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University
| Maryland
Holly Wilcox, PhD, MA
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Reduce Flare-Ups among People with Inflammatory Bowel Disease -- The QUOTIENT Study

University of California San Diego
| California
Siddharth Singh, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat PTSD among Veterans

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Keith Bredemeier, PhD, BA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Anxiety in Patients Who Go to the Emergency Room with Low-Risk Chest Pain

Trustees of Indiana University
| Indiana
Paul Musey, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Types of Well-Child Visits for Preventing Obesity among Preschool-Aged Children in Rural Areas

Geisinger Clinic
| Pennsylvania
Lisa Bailey-Davis, RD, DEd
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Manage Pain after High-Dose Chemotherapy

Memorial Sloan-Kettering Cancer Center
| New York
Gary Deng, MD, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center, Inc
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Standard and Family Diabetes Self-Management Education for Improving Diabetes Outcomes

University of Arkansas for Medical Sciences
| Arkansas
Pearl A. McElfish, PhD, MBA
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospital
| California
Katie Stone, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Perform Catheter Ablation to Treat Abnormal Heart Rhythms

The Regents of the University of California, San Francisco
| California
Gregory Marcus, MD, MAS
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Identify Sleep Apnea in People with Traumatic Brain Injury during Inpatient Rehabilitation

Tampa VA Research and Education Foundation
| Florida
Risa Nakase-Richardson, PhD, FACRM, FNAN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Treating Genital Herpes during Pregnancy Improve Birth Outcomes?

Kaiser Foundation Research Institute
| California
De-Kun Li, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Home, Clinic, and Kiosk Blood Pressure Checks for Diagnosing High Blood Pressure -- The BP-CHECK Study

Kaiser Permanente Washington Health Research Institute^
| Washington
Beverly B. Green, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Cognitive Behavioral Therapy versus Yoga for Helping Older Adults Address High Levels of Worry

Wake Forest University
| North Carolina
Gretchen A. Brenes, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Physical Therapy Schedules for Children with Cerebral Palsy -- The ACHIEVE Study

The Ohio State University
| Ohio
Jill C. Heathcock, MPT, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment for Ductal Carcinoma In Situ (DCIS) with or without Sentinel Lymph Node Biopsy

Yale University
| Connecticut
Shiyi Wang, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Antibiotics and Surgery to Treat Appendicitis in Children

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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