Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 51 - 75 of 249 results

Project Title
Project Status
Project Type

Comparing Two School Behavioral Health Programs to Improve Students' Academic Performance and Mental Health

University of South Carolina
| South Carolina
Mark Weist, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Offer Behavioral Therapy for Children with ADHD from Families with Low Incomes -- The PASS Study

Children's Hospital of Philadelphia
| Pennsylvania
Thomas Power, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Treatments for Dental Cavities in Older Adults Living in Low-Income Housing

Case Western Reserve University
| Ohio
Suchitra Nelson, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Ways to Promote Quitting Smoking for People Referred for Lung Cancer Screenings

University of Pennsylvania
| Pennsylvania
Scott Halpern, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Inpatient Versus Outpatient Settings for Treating Teens after a Suicidal Event

Cincinnati Children's Hospital Medical Center
| Ohio
Drew Barzman, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Remote Cognitive Behavior Therapy for Major Depression in Primary Care

University of South Florida
| Florida
Robert Bossarte, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Identify and Provide Care to Patients at Risk for Hereditary Cancer

Kaiser Foundation Research Institute
| California
Douglas Corley, MD, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Depression Prevention Programs for Teens -- The Path 2 Purpose Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Programs to Treat Patients with Inflammatory Bowel Disease and Behavioral Health Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Eva Szigethy, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

What Is the Effect of Adding a Health Coach to Patient-Centered Medical Homes for Managing Multiple Chronic Conditions?

Clinical Directors Network
| New York
Jonathan Tobin, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Supporting Shared Decision Making between Clinicians and Older Adults about Colorectal Cancer Screening -- The PRIMED Study

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD, and Leigh Simmons, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Online and In-Person Cognitive Behavioral Therapy in Youth with Anxiety Disorders -- The Kids FACE FEARS Study

Boston Medical Center Corporation
| Massachusetts
Donna Pincus
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Treat Childhood Obesity -- The TEAM UP Study

Washington University
| Missouri
Denise Wilfley, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Connecting Low-Income Tobacco Users with a Telephone Quitline to Help Them Quit

University of Utah
| Utah
David Wetter, PhD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Testing a Standard Approach to Match Patients with Addiction to Treatment Based on Their Needs -- The PCAST Study

RTI International
| North Carolina
Tami L. Mark, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Train Healthcare Clinic Staff to Ask Patients about Sexual Orientation and Gender Identity

Fenway Community Health Center
| Massachusetts
Kenneth H. Mayer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Treat Insomnia among Black Women

Boston University
| Massachusetts
Lynn Rosenberg, ScD, MS, and Eric Zhou, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Strategies for Health Clinics to Increase HPV Vaccinations in Youth

UCLA School of Public Health
| California
Roshan Bastani, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Cognitive Behavioral Therapy with Peer-Led Support Groups for Patients with Chronic Pain Who Want to Reduce Opioid Use -- The EMPOWER Study

Stanford University School of Medicine
| California
Beth Darnall, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two School-Based Programs to Prevent Dental Cavities in Communities with Fewer Resources and Hispanic Communities

New York University College of Dentistry
| New York
Richard Niederman, DMD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Two Antiseptic Skin Solutions to Prevent Infection in Patients Having Surgery to Treat Fractures -- The PREPARE Study

University of Maryland, Baltimore
| Maryland
Gerard P. Slobogean, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

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