Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 139 results

Project Title
Project Status
Project Type

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research

Perioperative Physical Activity in Older Adults Undergoing Lung Cancer Surgery

City of Hope Beckman Research Institute
| California
Dan Raz, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Prevent Falls among Patients with Cirrhosis of the Liver

University of Michigan
| Michigan
Elliot Tapper, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Healthcare Visit Recording and Open Notes to Improve the Chronic Illness Care Experience for Older Adults (The CHRONICLE Trial)

Trustees of Dartmouth College
| New Hampshire
Paul Barr, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Statistical Methods for Optimizing Dynamic Patient-Level Treatment and Monitoring Strategies

Rutgers University School of Public Health
| New Jersey
Jason Roy, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving PCOR/CER Study Methodologies in Studies with Different Respondent Types Using IRT

Brown University
| Rhode Island
Roee Gutman, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Pragmatic Comparative Effectiveness Using Sequential Multiple Assignment Randomized Trials

University of Rochester
| New York
Abdus Wahed, PhD, MS, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods for Analyzing Clustered Observational Data When Death is a Semi-Competing Risk

The University of Texas Southwestern Medical Center
| Texas
Hong Zhu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Types of Medicine for Pain after Surgery -- The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Screening Tests for Colon Cancer in Older Adults with a History of Colon Polyps -- The COOP Study

Dartmouth-Hitchcock Clinic
| New Hampshire
Audrey Calderwood, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Expanding the Use of Reports That Capture Age-Related Problems to Improve Doctor-Patient Conversations in Community Cancer Clinics

The University of Texas MD Anderson Cancer Center
| Texas
Lisa Lowenstein, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Manage Lymphedema among Head and Neck Cancer Survivors

The Trustees of The University of Pennsylvania
| Pennsylvania
Jie Deng, PhD, MSN, RN
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways of Providing Supportive Cancer Care to Adults with Cancer

The Board of Trustees of the Leland Stanford Junior University
| California
Manali Patel, MD, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Enrollment complete
Project Type:
Research

Testing a Program to Improve Quality of Life among Latina Breast Cancer Survivors and Their Partners

University of South Florida
| Florida
Dinorah Martinez Tyson, PhD, MPH, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Supporting Families' Treatment Decisions with Evidence on Treatment of Urea Cycle Disorders

Children's National Health System
| District of Columbia
Nicholas Ah Mew, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Dissemination Project (Limited Competition D&I PFA)

Emerging Technologies and Therapeutics Reports: Genomic Sequencing to Guide Cancer Management

ECRI
| Pennsylvania
Project Status:
Completed
Project Type:
Other Evidence Products

Emerging Technologies and Therapeutics Reports: Narrative Review and Evidence Mapping of Proteomics for Cancer and Cardiovascular Disease

RAND Corporation
| California
Project Status:
Completed
Project Type:
Other Evidence Products

Emerging Technologies and Therapeutics Reports: Narrative Review and Evidence Mapping of Artificial Intelligence in Clinical Care

RAND Corporation
| California
Project Status:
Completed
Project Type:
Other Evidence Products

Comparing Three Ways to Offer Social Support to Black Women during Treatment for Endometrial Cancer

University of Washington
| Washington
Kemi Doll, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparative Effectiveness Trial of Perioperative Telemonitoring for Functional Recovery and Symptoms

City of Hope
| California
Virginia Sun, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

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