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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 43 results

Project Title
Project Status
Project Type

A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum

The University of North Carolina at Chapel Hill
| North Carolina
Brenna Maddox, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Achieving Blood Pressure Goals after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Evaluation of Telehealth Services on Mental Health Outcomes for People With Intellectual and Developmental Disabilities

University of New Hampshire
| New Hampshire
Joan Beasley, PhD, MEd
Project Status:
In progress; Not yet recruiting
Project Type:
Research

BEhavioral Health Stratified Treatment (BEST) to Optimize Transition to Adulthood for Youth with IDD

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparative Effectiveness of Palliative Surgery versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Sandi Lam
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Teletherapy to Address Language Disparities in Deaf and Hard-of-Hearing Children

The Regents of the University of California, San Francisco
| California
Dylan Chan, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Elders Preserving Independence in the Community (EPIC)

Cedars-Sinai
| California
Harriet Aronow, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Improve Communication between Healthcare Teams and People with a Communication Disability

University of Colorado Denver
| Colorado
Megan A. Morris, PhD, MPH, CCC-SLP
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Cognitive Behavioral Therapy with Peer-Led Support Groups for Patients with Chronic Pain Who Want to Reduce Opioid Use -- The EMPOWER Study

Stanford University School of Medicine
| California
Beth Darnall, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing a Multiple Sclerosis Fatigue Management Course Delivered via Teleconference, Internet, or in Person

Case Western Reserve University
| Ohio
Matthew A. Plow, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Home and Facility-Based Exercise to Improve Mobility in People with Multiple Sclerosis -- STEP for MS

Shepherd Center
| Georgia
Deborah A. Backus, PhD, PT
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Examining Whether Early Aggressive Therapy Can Prevent or Delay Disability in People with Multiple Sclerosis: the TREAT-MS Study

Johns Hopkins University
| Maryland
Ellen M. Mowry, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatments for Fatigue in Patients with Multiple Sclerosis -- COMBO-MS

University of Michigan
| Michigan
Tiffany Braley, MD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Approaches to Treat Relapsing-Remitting Multiple Sclerosis -- the DELIVER-MS Study

Cleveland Clinic Foundation
| Ohio
Daniel Ontaneda, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Does Reporting Symptoms Between Doctor Visits Improve Length and Quality of Life in Patients with Advanced Cancer?

The Alliance for Clinical Trials In Oncology Foundation
| Illinois
Ethan Basch, MD, TRD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Safety and Effectiveness of Medicines Patients Take for Many Years to Treat Multiple Sclerosis (MS) -- The COMBAT-MS Study

Karolinska Institute (Sweden)
Fredrik Piehl, MD, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study

Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods to Identify and Predict Which Patients Will Have High Healthcare Needs and Use -- A PCORnet® Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Examining the Effectiveness of Case Management Programs on Preventing Hospital Stays in Older Adults with Multiple Chronic Health Problems -- A PCORnet® Study

University of Wisconsin-Madison
| Wisconsin
Maureen A. Smith, MD, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Physical Therapy Schedules for Children with Cerebral Palsy -- The ACHIEVE Study

The Ohio State University
| Ohio
Jill C. Heathcock, MPT, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Web-Based Platform for Caregivers Help People with Down Syndrome Get Recommended Health Services?

Massachusetts General Hospital
| Massachusetts
Brian Skotko, MD, MPP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Medicines to Prevent Chronic Obstructive Pulmonary Disease Episodes -- The RELIANCE Study

University of Illinois at Chicago
| Illinois
Jerry A. Krishnan, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Testing a Program That Provides Care for Urgent Health Problems at Home Instead of the Emergency Room

Massachusetts General Hospital
| Massachusetts
Lisa I. Iezzoni, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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