Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Displaying 26 - 50 of 889 results

Project Title
Project Status
Project Type

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

Trustees of Indiana University
| Indiana
Zachary Adams, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of Brief Motivational Interviewing With and Without Adjunctive App-Delivered Mindfulness Training for Reducing Alcohol Use Among Adolescents in Pediatric Primary Care

Johns Hopkins University School of Medicine
| Maryland
Christopher Hammond, M.D., Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

The Dose Trial: Dose Intensity for Behavioral Interventions for Childhood Obesity

Vanderbilt University Medical Center
| Tennessee
William Heerman, M.D., MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Remote Hypertension Tracking Help and Management to Reduce Disparities in Black Patients (RHYTHM-B)

Wake Forest University Health Sciences
| North Carolina
Yhenneko Taylor, Ph.D., Mstat
Project Status:
Awarded; Contract pending
Project Type:
Research

Home-Based Pulmonary Rehabilitation With Health Coaching in Patients With Fibrotic Lung Disease

Mayo Clinic Rochester
| Minnesota
Teng Moua, M.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Mindfulness-Based Interventions for Mental Health in Children and Adolescents (A Systematic Review)

Agency for Healthcare Research and Quality (AHRQ)
| Maryland
Project Status:
Ongoing
Project Type:
Research

Improving Outcomes for Patients with Multiple Chronic Conditions Using ECHO

University of New Mexico Health Sciences Center
| New Mexico
Sanjeev Arora, M.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Peer Support Enhanced Behavioral Crisis Response Teams in the Emergency Department

Yale University
| Connecticut
Ambrose Wong, M.D., M.Ed., MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Reducing Future Fractures and Improving Outcomes of Fragility Fracture -- The RESTORE Study

The University of Alabama at Birmingham
| Alabama
Kenneth Saag, M.D., M.Sc.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

DECIDE: A Comparative Effectiveness Trial of Oral Metformin versus Injectable Insulin for the Treatment of Gestational Diabetes

The Ohio State University
| Ohio
Mark Landon, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comorbidity of Chronic Pain and Early Cognitive Decline Among Older, Community-Based Black Adults: Comparative Effectiveness of Mindfulness-Based Cognitive Therapy with walking (MBCT) versus Active Living Every Day (ALED)

Massachusetts General Hospital
| Massachusetts
Olivia Okereke, A.B., M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Models of Post-Acute Care in Complex Older Adults with Fracture

Duke University School of Medicine
| North Carolina
Cathleen Colon-Emeric, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Optimizing Childhood Obesity and Asthma Outcomes in Primary Care via Telehealth

Massachusetts General Hospital
| Massachusetts
Lauren Fiechtner, M.D., MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Enhanced Primary Telecare versus Consultative Complex Care for Children with Medical Complexity

Wake Forest School of Medicine
| North Carolina
Savithri Nageswaran, M.D., MPH, MBBS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Pragmatic Trial Comparing the Effectiveness of Ketamine versus Etomidate for Intubation

Vanderbilt University Medical Center
| Tennessee
Matthew Semler, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Activating SilverSneakers Benefits for Seniors with Osteoarthritis: Proactive versus Usual Care

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Liza Rovniak, Ph.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Revascularization Choices Among Under-Represented Groups Evaluation (The RECHARGE Program)

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Mario Gaudino, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Annual Wellness Visits versus GRACE-augmented Annual Wellness Visits for Older Adults with High Needs

Massachusetts General Hospital
| Massachusetts
Christine Ritchie, M.D., MSPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Generalist versus Specialist Palliative Care for Inpatients

University of Pennsylvania
| Pennsylvania
Scott Halpern, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparative Effectiveness of Lifestyle Interventions for Older Cancer Survivors and Their Caregivers

Dana-Farber Cancer Institute
| Massachusetts
Christina Dieli-Conwright, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Trial of Sequential Medications AfteR TNF failure in Juvenile Idiopathic Arthritis (SMART-JIA)

Duke University
| North Carolina
Laura Schanberg, M.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Functional improvement in Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease with a Telehealth LifeStyle and Exercise Intervention (FOCuSEd)

Seattle Institute for Biomedical and Clinical Research
| Washington
Laura Feemster, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Oral Drug Dosing Strategies in Older Patients with Metastatic Breast Cancer to Maximize Tolerance and Reduce Discontinuation: The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

American Society of Clinical Oncology
| Virginia
Julie Gralow, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Improving Cardiovascular Health in Polycystic Ovary Syndrome

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Anuja Dokras, M.D., Ph.D., MHCI
Project Status:
Awarded; Contract pending
Project Type:
Research

Measuring Co-Creation During the Engagement Process in Research: A Pathway Forward

University of Colorado Denver
| Colorado
Monica Perez Jolles, Ph.D., M.A.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

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