Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 24 of 24 results

Project Title
Project Status
Project Type

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Expanding a Program to Help Clinics and Families Take Steps to Reduce Childhood Obesity

Massachusetts General Hospital
| Massachusetts
Elsie Taveras, MD, MPH
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)
Has Results

Does a Decision Aid Help Older Adults with Chronic Kidney Disease Choose Treatment? -- The DART Study

Trustees of Tufts College
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Approaches to Improve Black Patients’ Chances of Getting Live Donor Kidney Transplants

Beth Israel Deaconess Medical Center, Inc
| Massachusetts
James R. Rodrigue, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Using a Prediction Model to Identify Patients Who Can Benefit from Diabetes Prevention

Tufts Medical Center
| Massachusetts
David Kent, MD, MS
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)
Has Results

Comparing the Benefits and Harms of Different Long-Term Treatments for Blood Clots -- The DARE Warfarin Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Katsiaryna Bykov, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Preferences for Depression and Diabetes Treatment among Adults of Different Racial and Ethnic Groups Who Reported Discrimination in Health Care

Cambridge Health Alliance
| Massachusetts
Benjamin Cook, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Helping People with Serious Mental Illness Stop Smoking

Massachusetts General Hospital
| Massachusetts
Eden Evins, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity

Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Looking at the Effects of Antibiotic Use on Childhood Obesity and Growth -- The PCORnet® Antibiotics Study

Harvard Pilgrim Health Care, Inc.
| Massachusetts
Jason Block, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Testing an Online Program with and without Health Management Support to Help Patients Manage Their Weight

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Effect of High-Deductible Health Plans on Healthcare Use and Out-of-Pocket Costs for People with Bipolar Disorder

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
James Franklin Wharam, MB, BCh, BAO, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Statistical Methods to Preserve Patient Privacy When Sharing and Analyzing Data

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Darren Toh, ScD, BPHAR, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Ask Patients about Sexual Orientation and Gender Identity in the Emergency Room -- The EQUALITY Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Adil Haider, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can an Online Program Help Women with a History of Preeclampsia Reduce Their Risk of Heart Disease?

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Janet Rich-Edwards, MPH, ScD, and Ellen W. Seely, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Do Weight Management Programs Involving Health Coaches Improve Body Mass Index and Parent Empowerment for Children with Obesity or Who Are Overweight?

Massachusetts General Hospital
| Massachusetts
Elsie Mireya Taveras, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Effect of End-of-Life Care Planning Discussions on Hospice Use among Patients Receiving Dialysis for Kidney Failure

Baystate Medical Center
| Massachusetts
Lewis Mitchel Cohen, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Including Patient Traits in Benchmarks for Diabetes Care

Harvard University School of Public Health
| Massachusetts
Marcia Anne Testa, BA, MPH, MPHIL, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating Home-Based Health Coaching from Community Health Representatives for Navajo Adults with Type 2 Diabetes

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Sonya Shin, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Program that Focuses on Lifestyle Changes Reduce Heart Disease Risk Factors in a Rural Community in Appalachian Kentucky?

University of Kentucky
| Kentucky
Debra K. Moser, PhD, RN, FAAN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Predicted Benefits and Harms of Using Adult versus Child Guidelines for Lipid Testing and Treatment in 17- to 21-Year-Olds

Tufts Medical Center, Inc.
| Massachusetts
Laurel K. Leslie, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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