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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 93 results

Project Title
Project Status
Project Type

Randomized Trials and Their Observational Emulations -- Benchmarking and Join Analysis

President and Fellows of Harvard College
| Massachusetts
Issa Dahabreh, MD, ScD, MS
Project Status:
Awarded; Contract pending
Project Type:
Research

Expanding First-Line Options for Depression & Matching Treatments: Hatha Yoga vs. Behavioral Therapy

Massachusetts General Hospital
| Massachusetts
Louisa Sylvia, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

Specialty Compared to Oncology delivered Palliative Care for Patients with Acute Myeloid Leukemia (SCOPE-Leukemia)

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

PRECIDENTD (PREvention of CardIovascular and DiabEtic kidNey disease in Type 2 Diabetes)

Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

BESTMED: Observational Evaluation of Second-Line Therapy Medications in Diabetes

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Treatment for Opioid Use Disorder before and during the COVID-19 Pandemic

Boston VA Research Institute, Inc.
| Massachusetts
Nicholas Livingston, PhD and Risa Weisberg, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Programs to Decrease HIV Risk among African-Born Black Women

Brigham and Women's Hospital
| Massachusetts
Bisola Ojikutu, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research
Has Results

Patent Foramen Ovale Closure after Cryptogenic Stroke: Meta-Analysis and Risk Modeling Using Pooled Individual Patient Data from Six Trials

Tufts Medical Center Inc.
| Massachusetts
David M. Kent, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Toward a New Generation of Matching Methods for Comparative Effectiveness Research

Harvard Medical School
| Massachusetts
Jose R. Zubizarreta, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods to Improve the Accuracy of Data Obtained from Clinicians' Notes in Electronic Health Records

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Help Clinicians and Older Patients Make Colorectal Cancer Screening Decisions

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Online and In-Person Cognitive Behavioral Therapy in Youth with Anxiety Disorders -- The Kids FACE FEARS Study

Boston Medical Center Corporation
| Massachusetts
Donna Pincus
Project Status:
In progress; Recruiting
Project Type:
Research

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression (CEPIO-D)

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Help Patients with Chronic Kidney Disease and Their Care Partners Choose among Treatment Options -- The DART Study

Tufts University
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
In progress; Enrollment complete
Project Type:
Research

How Does Training Healthcare Providers to Discuss Sexual Orientation and Gender Identity Affect Care?

Fenway Community Health Center
| Massachusetts
Kenneth Mayer, MD
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Treat Insomnia among Black Women

Trustees of Boston University, BUMC
| Massachusetts
Lynn Rosenberg, ScD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Understanding How Gender Affirmation Therapies Affect HIV-Related Health for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari Reisner, ScD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Ways to Provide Palliative Care for Patients with Advanced Lung Cancer

Massachusetts General Hospital
| Massachusetts
Jennifer S. Temel, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Developing New Methods for Comparing Treatments in Case-Control Studies

Harvard T.H. Chan School of Public Health
| Massachusetts
Goodarz Danaei, MD, MS, DSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Approaches to Improve Black Patients’ Chances of Getting Live Donor Kidney Transplants

Beth Israel Deaconess Medical Center
| Massachusetts
James R. Rodrigue, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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