Explore Our Portfolio
Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio |
Displaying 1 - 25 of 32 results
Project Title
Project Status
Project Type
Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD
Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research
Has Results
Comparing Two Ways to Help Sexual and Gender Minority Men Who Have Been Sexually Abused Reduce Depression and Increase Mental Health Treatment Engagement
Yale University
| Connecticut
Joan M. Cook, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Comparing Two Programs for Managing Long-Term Health Problems for People with Lived Experience of Mental Illness
Dartmouth-Hitchcock Clinic
| New Hampshire
Sarah Pratt, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results
Comparing a Multiple Sclerosis Fatigue Management Course Delivered via Teleconference, Internet, or in Person
Case Western Reserve University
| Ohio
Matthew A. Plow, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Comparing Home and Facility-Based Exercise to Improve Mobility in People with Multiple Sclerosis -- STEP for MS
Shepherd Center
| Georgia
Deborah A. Backus, PhD, PT
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Examining Whether Early Aggressive Therapy Can Prevent or Delay Disability in People with Multiple Sclerosis: the TREAT-MS Study
Johns Hopkins University
| Maryland
Ellen M. Mowry, MD, MCR
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial
University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Comparing Two Approaches to Treat Relapsing-Remitting Multiple Sclerosis -- the DELIVER-MS Study
Cleveland Clinic Foundation
| Ohio
Daniel Ontaneda, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results
Comparing Two Approaches for Delivering Group Medical Visits for Patients with Diabetes
University of Colorado Denver
| Colorado
Bethany M. Kwan, PhD, MSPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Comparing Two Oral Medicines to Improve Patient Experiences with Relapsing-Remitting Multiple Sclerosis -- PRAG-MS
Fondazione IRCCS Istituto Neurologico "Carlo Besta" (Italy)
| N/A
Renato Mantegazza, MD^
Project Status:
Terminated
Project Type:
Research
Comparing Clinic- and Home-Based Exercise Programs to Help Adults with Multiple Sclerosis -- The TEAMS Study
University of Alabama at Birmingham
| Alabama
James Rimmer, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study
Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study
Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Standard and Short Online Mindfulness Therapy Programs for Improving Well-Being -- The Healthy Mind Healthy You Study
Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Comparing Medicines for Long-Term Treatment of Bipolar Disorder
University of New Mexico Health Sciences Center
| New Mexico
Christophe G. Lambert, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Three Ways to Increase Physical Activity in Patients with Depression and Cardiovascular Disease -- The Healthy Hearts Healthy Minds Study
Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Helping People with Serious Mental Illness Stop Smoking
Massachusetts General Hospital
| Massachusetts
Eden Evins, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing Stopping or Continuing Use of Disease Modifying Therapies in Older Adults with Multiple Sclerosis -- The DISCOMS Trial
University of Colorado Denver
| Colorado
John R. Corboy, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Matching Patients with Therapists to Improve Mental Health Care
University of Massachusetts Amherst
| Massachusetts
Michael J. Constantino, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Two Telehealth Approaches for Treating Complex Psychiatric Disorders in Primary Care -- The SPIRIT Study
University of Washington
| Washington
John C. Fortney, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Effect of High-Deductible Health Plans on Healthcare Use and Out-of-Pocket Costs for People with Bipolar Disorder
Harvard Pilgrim Health Care ,Inc.
| Massachusetts
James Franklin Wharam, MB, BCh, BAO, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Ways to Manage Weight and Overall Health in Overweight and Obese Youth with Bipolar Spectrum Disorders Who Take Antipsychotic Medicines -- The MOBILITY Study
University of Cincinnati
| Ohio
Melissa P. DelBello, MD, MS
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results
Developing Measures of Pain Appraisal and Pain-Related Self-Efficacy for People Living with Chronic Pain
University of Washington
| Washington
Dagmar Amtmann, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing a Smartphone Program with a Peer-Led Program to Help People with Serious Mental Illness Manage Their Symptoms
University of Washington^
| Washington
Dror Ben-Zeev, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Peer-Navigator Support for Latinx Patients with Serious Mental Illness
Illinois Institute of Technology
| Illinois
Patrick William Corrigan, PsyD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research