Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 34 results

Project Title
Project Status
Project Type

Comparing Two Types of Medicine for Pain after Surgery -- The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Manage Pain after High-Dose Chemotherapy

Memorial Sloan-Kettering Cancer Center
| New York
Gary Deng, MD, PhD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Acupressure on Cancer Treatment Side Effects in Children and Youth -- The ACT-CC Study

University of California San Francisco
| California
E. Anne Lown, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment for Ductal Carcinoma In Situ (DCIS) with or without Sentinel Lymph Node Biopsy

Yale University
| Connecticut
Shiyi Wang, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Types of Blood Thinners to Prevent Blood Clots in Patients with Cancer -- The CANVAS Trial

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Deborah Schrag, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatment Approaches for Women with Ductal Carcinoma In Situ (DCIS) -- The PORTAL Study

Duke University
| North Carolina
E. Shelley Hwang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of How Often Men Have PSA Testing in the First Year after Prostate Cancer Treatment

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Ronald C. Chen, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Chemotherapy Recovery at Home versus in the Hospital for Children with Acute Myeloid Leukemia

The Children's Hospital of Philadelphia
| Pennsylvania
Richard Aplenc, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Surgeries for Women Who Have Both Cancer of the Uterus and Bladder Problems

Women & Infants Hospital of Rhode Island
| Rhode Island
Katina Robison, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Clinician-Collected and Self-Collected Tests for Detecting High-Risk HPV Infection among Female-to-Male Transgender Adults

Fenway Community Health Center
| Massachusetts
Sari Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Acupuncture and Cognitive Behavioral Therapy to Treat Insomnia among Cancer Survivors -- The CHOICE Trial

Sloan Kettering Institute for Cancer Research^
| New York
Jun James Mao, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Different Prostate Cancer Treatments on Quality of Life and Cancer Recurrence -- NC ProCESS

University of North Carolina at Chapel Hill
| North Carolina
Ronald C. Chen, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Is Breast MRI Better at Finding Second Breast Cancers than Mammograms Alone for Breast Cancer Survivors?

Kaiser Permanente Washington Health Research Institute^
| Washington
Karen Joanne Wernli, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using a Program to Lower Stress for Caregivers of Patients with Cancer Who Have Received Stem Cell Transplants

University of Colorado Denver
| Colorado
Mark L. Laudenslager, BA, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

How Do Preferences for Treatment Change after Patients with Lung Cancer Start Chemotherapy?

University of Nebraska Medical Center
| Nebraska
KM Islam, MBBS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

A Patient Decision Aid to Help Heavy Smokers Make Decisions about Lung Cancer Screening

University of Texas MD Anderson Cancer Center
| Texas
Robert J. Volk, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Improving Informed Consent for Palliative Chemotherapy

Dana-Farber Cancer Institute
| Massachusetts
Deborah Schrag, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Treatment Decision Support for Men with Prostate Cancer and Their Caregivers

H. Lee Moffitt Cancer Center & Research Institute
| Florida
Lee Green, PhD^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Intensity of Follow-Up Tests after Surgery for Colorectal Cancer

Alliance for Clinical Trials in Oncology Foundation
| Illinois
George J. Chang, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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