Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 26 - 50 of 84 results

Project Title
Project Status
Project Type

Developing Methods for Combining and Analyzing Electronic Health Record Data

University of Pennsylvania
| Pennsylvania
Yong Chen, PhD, MA
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Manage Diabetes among African-American Women in the Southeast

Meharry Medical College
| Tennessee
Stephania Miller-Hughes, PhD, MS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

The HERO Research Program -- A PCORnet® Project to Support Studies on COVID-19

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Provide Follow-Up Care to Patients with Heart Failure after Hospital Discharge -- MIGHTY-Heart

The Trustees of Columbia University in the City of New York
| New York
Ruth Masterson Creber, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Developing Methods to Improve the Accuracy of Data Obtained from Clinicians' Notes in Electronic Health Records

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Improving Methods for Extracting Data from Clinicians' Notes in Electronic Health Records

Medical University of South Carolina
| South Carolina
Paul M. Heider, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Improving Methods for Identifying Social, Behavioral, and Clinical Factors in Doctors' Notes in Electronic Health Records

University of Florida
| Florida
Yonghui Wu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Developing Methods to Identify Patients Who Benefit Most from Different Treatments

University of Pennsylvania
| Pennsylvania
Yong Chen, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospital
| California
Katie Stone, PhD, MA
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Using PCORnet to Track Patient-Reported Symptoms of Heart Failure

Vanderbilt University Medical Center
| Tennessee
Justin Bachmann, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Promote Healthy Weight Gain and Prevent Obesity in Early Childhood

Vanderbilt University Medical Center
| Tennessee
William J. Heerman, MD, MPH^
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

A New Natural Language Processing Method to Study Whether Patients Take Medicine as Directed

The University of Texas Health Science Center at Houston
| Texas
Kirk Roberts, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Inpatient Versus Outpatient Settings for Treating Teens after a Suicidal Event

Cincinnati Children's Hospital Medical Center
| Ohio
Drew Barzman, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways for Hospitals to Help Patients Recover During and After Stroke

Vanderbilt University Medical Center
| Tennessee
Kenneth Gaines, MD, MBA
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Identify and Provide Care to Patients at Risk for Hereditary Cancer

Kaiser Foundation Research Institute
| California
Douglas Corley, MD, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

What Is the Effect of Adding a Health Coach to Patient-Centered Medical Homes for Managing Multiple Chronic Conditions?

Clinical Directors Network
| New York
Jonathan Tobin, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Treat Childhood Obesity -- The TEAM UP Study

Washington University
| Missouri
Denise Wilfley, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Abatacept to Usual Care for Preventing Disease Worsening in Juvenile Idiopathic Arthritis

Duke University
| North Carolina
Laura Schanberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression (CEPIO-D)

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatments for Chronic Low Back Pain

University of Utah
| Utah
Julie Fritz, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

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