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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 140 results

Project Title
Project Status
Project Type

Comparing Analgesic Regimen Effectiveness and Safety After Surgery – The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
Awarded; Contract pending
Project Type:
Research

Music Therapy vs. Cognitive-Behavioral Therapy for Cancer-related Anxiety (MELODY)

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Treat-to-Target of Endoscopic Remission in Patients with Inflammatory Bowel Diseases in Symptomatic Remission: A Pragmatic Randomized Controlled Trial

University of California San Diego
| California
Siddharth Singh, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

A Real-World Comparative Effectiveness Trial of Treatment Strategies in Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Biologic Abatement and Capturing Kids? Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA)

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD: What Works Best and For Whom

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Keith Bredemeier, PhD, BA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Anxiety in Patients Who Go to the Emergency Room with Low-Risk Chest Pain

Trustees of Indiana University
| Indiana
Paul Musey, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Types of Well-Child Visits for Preventing Obesity among Preschool-Aged Children in Rural Areas

Geisinger Clinic
| Pennsylvania
Lisa Bailey-Davis, RD, DEd
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Manage Pain after High-Dose Chemotherapy

Memorial Sloan-Kettering Cancer Center
| New York
Gary Deng, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Standard and Family Diabetes Self-Management Education for Improving Diabetes Outcomes

University of Arkansas for Medical Sciences
| Arkansas
Pearl A. McElfish, PhD, MBA
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Provide Pregnant Women with Prenatal Care and Treatment for Opioid Use Disorder

Yale University School of Medicine
| Connecticut
Ariadna Forray
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Insomnia in Adults Living in Rural Areas

Sutter Bay Hospitals
| California
Katie Stone, PhD, MA
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- CaRISMA

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Perform Catheter Ablation to Treat Abnormal Heart Rhythms

The Regents of the University of California, San Francisco
| California
Gregory Marcus, MD, MAS
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Medicines for Treating Type 2 Diabetes among Patients with Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
Alvin Mushlin, MD, ScM
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Methods to Deliver a Health Education Program for Pregnant Women Treated for Opioid Use Disorder in Rural Kentucky -- The PATH Home Trial

University of Kentucky Research Foundation
| Kentucky
Wendy Hansen, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Treatment for Pregnant Women with Opioid Use Disorder

Trustees of Dartmouth College
| New Hampshire
Sarah Lord, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Hair Removal Treatments for Adolescents with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter Minneci, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Meditation with Medicine for Patients with Anxiety Disorders

Georgetown University Medical Center
| District of Columbia
Elizabeth Hoge, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Does Adding Acupuncture and/or Pain Counseling to Pain Medicine Help Reduce Pain Among Hospitalized Patients with Cancer?

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

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