Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Displaying 1 - 25 of 28 results

Project Title
Project Status
Project Type

My Anesthesia Choice: Implementing an Evidence-Based Approach to Increase Shared Decision Making

University of Pennsylvania
| Pennsylvania
Mark Neuman, M.D., M.S.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Promoting Shared Decision Making About Colorectal Cancer Testing in Older Adults

The General Hospital Coporation d/b/a Massachusetts General Hospital
| Massachusetts
Karen Sepucha, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Revascularization Choices Among Under-Represented Groups Evaluation (The RECHARGE Program)

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Mario Gaudino, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Annual Wellness Visits versus GRACE-augmented Annual Wellness Visits for Older Adults with High Needs

Massachusetts General Hospital
| Massachusetts
Christine Ritchie, M.D., MSPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Generalist versus Specialist Palliative Care for Inpatients

University of Pennsylvania
| Pennsylvania
Scott Halpern, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Trial of Sequential Medications AfteR TNF failure in Juvenile Idiopathic Arthritis (SMART-JIA)

Duke University
| North Carolina
Laura Schanberg, M.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Putting a Decision Aid into Practice to Support Shared Decision Making for Colorectal Cancer Screening

Trustees of Indiana University
| Indiana
Peter Schwartz, M.D., Ph.D.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Sinusitis

Georgetown University Medical Center
| District of Columbia
Daniel Merenstein, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Pacing Treatments for Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD

Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Individualizing Treatment for Asthma in Primary Care

DARTNet Institute
| Kansas
Wilson Pace, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Screening Tests for Colon Cancer in Older Adults with a History of Colon Polyps -- The COOP Study

Dartmouth-Hitchcock Clinic
| New Hampshire
Audrey Calderwood, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Anesthesia for Surgery -- The THRIVE Trial

Regents of the University of Michigan
| Michigan
Sachin Kheterpal, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Supporting Ongoing Use of Two Conversation Aids for Making Decisions about Early-Stage Breast Cancer Treatment -- The SHAIR Collaborative

Trustees of Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, MSc
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Putting a Diabetes Risk Prediction Tool into Practice to Support Shared Clinical Decision Making

The Regents of the University of California, Los Angeles
| California
O. Kenrik Duru, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Shared Decision Making for Weight Loss Surgery in Patients with Severe Obesity

Kaiser Foundation Health Plan of Washington
| Washington
David Arterburn, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)
Has Results

Comparing Two Programs to Reduce Unsafe Opioid Prescribing and Improve Outcomes among People Who Are Injured at Work -- The WOW Study

University of Washington
| Washington
Gary Franklin, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Improving Shared Decision Making for Men with Early-Stage Prostate Cancer

Regents of the University of California, Los Angeles
| California
Christopher Saigal, MD, MPH
Project Status:
Completed
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Expanding Use of a Decision Aid to Help People with Lupus Nephritis Make Decisions about Treatment

University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Using a Decision Aid to Help Patients Make Decisions about Treatment for Fibroids

Trustees of Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, FRCGP, MSc, MB BCh
Project Status:
Completed
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

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