Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 32 results

Project Title
Project Status
Project Type

Effectiveness of a Multimodal Intervention for Transitions of Care after Lower Limb Fracture

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Patricia Dykes, PhD, RN, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center, Inc
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Supporting Shared Decision Making between Clinicians and Older Adults about Colorectal Cancer Screening -- The PRIMED Study

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD, and Leigh Simmons, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Online and In-Person Cognitive Behavioral Therapy in Youth with Anxiety Disorders -- The Kids FACE FEARS Study

Boston Medical Center Corporation
| Massachusetts
Donna Pincus
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression (CEPIO-D)

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Does a Decision Aid Help Older Adults with Chronic Kidney Disease Choose Treatment? -- The DART Study

Trustees of Tufts College
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Train Healthcare Clinic Staff to Ask Patients about Sexual Orientation and Gender Identity

Fenway Community Health Center
| Massachusetts
Kenneth H. Mayer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Treat Insomnia among Black Women

Boston University
| Massachusetts
Lynn Rosenberg, ScD, MS, and Eric Zhou, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Ways to Provide Palliative Care for Patients with Advanced Lung Cancer

Massachusetts General Hospital
| Massachusetts
Jennifer S. Temel, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Messaging Systems to Increase Use of Online Programs That Help Smokers Quit -- Smoker-to-Smoker (S2S)

University of Massachusetts Medical School
| Massachusetts
Rajani Sadasivam, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways to Provide Follow-Up Care to Patients after Bone Marrow Transplants

Dana-Farber Cancer Institute
| Massachusetts
Gregory Abel, MD, MPH
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Improving Methods for Analyzing Data from Case-Only Studies

President & Fellows of Harvard College
| Massachusetts
Murray A. Mittleman, MD, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Web-Based Platform for Caregivers Help People with Down Syndrome Get Recommended Health Services?

Massachusetts General Hospital
| Massachusetts
Brian Skotko, MD, MPP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Increase Physical Activity in Patients with Depression and Cardiovascular Disease -- The Healthy Hearts Healthy Minds Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Evaluating Different Ways to Help Patients Make Informed Choices about Surgery for Knee or Hip Osteoarthritis

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity

Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Testing an Online Program with and without Health Management Support to Help Patients Manage Their Weight

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Communication Training Programs for Cancer Doctors

Dana-Farber Cancer Institute
| Massachusetts
James Tulsky, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Monitoring Oxygen Levels of Premature Babies at Home and in the Clinic -- The RHO Trial

University of Massachusetts Medical School^
| Massachusetts
Lawrence Rhein, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Preventing Serious Falls among Older Adults -- The STRIDE Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Shalender Bhasin, MD, MB, BS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Ask Patients about Sexual Orientation and Gender Identity in the Emergency Room -- The EQUALITY Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Adil Haider, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can an Online Program Help Women with a History of Preeclampsia Reduce Their Risk of Heart Disease?

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Janet Rich-Edwards, MPH, ScD, and Ellen W. Seely, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Improving Informed Consent for Palliative Chemotherapy

Dana-Farber Cancer Institute
| Massachusetts
Deborah Schrag, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Smartphone App Help Patients with Cancer Take Oral Chemotherapy as Planned?

Massachusetts General Hospital
| Massachusetts
Joseph A. Greer, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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