Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 35 results

Project Title
Project Status
Project Type

Patient-Level Artificial Intelligence to Derive Longitudinal Phenotypes for Comparative Clinical Effectiveness Research

Dana-Farber Cancer Institute
| Massachusetts
Kenneth Kehl, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Learning to Predict Disease Trajectories

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Mei-Sing Ong, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Identification of Temporal Data Patterns Predictive of Adverse Outcomes in Patients with Diabetes

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Fast and Robust Weighting Methods for Targeted Comparative Effectiveness Research

President and Fellows of Harvard College
| Massachusetts
Jose Zubizarreta, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Transportability of Machine Learning-Enabled Confounding Control Methods Across EHR Databases

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Richard Wyss, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving Methods for Benchmarking and Joint Analysis for Observational Studies

President and Fellows of Harvard College
| Massachusetts
Issa Dahabreh, MD, ScD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods for Analyzing Clustered Observational Data When Death is a Semi-Competing Risk

The University of Texas Southwestern Medical Center
| Texas
Hong Zhu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Treatment for Opioid Use Disorder before and during the COVID-19 Pandemic

Boston VA Research Institute, Inc.
| Massachusetts
Nicholas Livingston, PhD and Risa Weisberg, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Toward a New Generation of Matching Methods for Comparative Effectiveness Research

Harvard Medical School
| Massachusetts
Jose R. Zubizarreta, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Developing Methods to Improve the Accuracy of Data Obtained from Clinicians' Notes in Electronic Health Records

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

A New Natural Language Processing Method to Study Whether Patients Take Medicine as Directed

The University of Texas Health Science Center at Houston
| Texas
Kirk Roberts, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

A New Statistical Method for Designing Stepped-Wedge Cluster Trials

University of Texas Southwestern Medical Center at Dallas
| Texas
Song Zhang, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Developing New Methods for Comparing Treatments in Case-Control Studies

Harvard T.H. Chan School of Public Health
| Massachusetts
Goodarz Danaei, MD, MS, DSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing Two Patient Surveys for Diagnosing Rare Genetic Conditions

Boston Children's Hospital
| Massachusetts
Ingrid A. Holm, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Different Data Sets to Test How Well Clinical Prediction Models Work to Predict Patients' Risk of Heart Disease

Tufts Medical Center
| Massachusetts
David M. Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing and Testing Software for Linking Patient Data from Multiple Sources

Texas A&M University Health Science Center
| Texas
Hye-Chung Kum, PhD, MSW, MS, FAMIA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Creating a New Process to Include Medical Device Information in Insurance Claims

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Joel S. Weissman, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Linking Randomized Clinical Trials and ClaiTRD Data for Enhancing Randomized and Non-Randomized Patient-Centered Outcomes Evidence Generation

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Mehdi Najafzadeh, PhD, MA, TRD
Project Status:
Awarded; Contract not executed
Project Type:
Research
Has Results

Using Visual Analytic Methods to Identify Patient Groups

The University of Texas Medical Branch at Galveston
| Texas
Suresh K. Bhavnani, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Preferences for Depression and Diabetes Treatment among Adults of Different Racial and Ethnic Groups Who Reported Discrimination in Health Care

Cambridge Health Alliance
| Massachusetts
Benjamin Cook, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing a Process for Getting Patient and Caregiver Input on Clinical Practice Guidelines

RAND Corporation
| Massachusetts
Dmitry Khodyakov, PhD, MA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Improving Methods for Analyzing Data from Case-Only Studies

President & Fellows of Harvard College
| Massachusetts
Murray A. Mittleman, MD, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing Guidance for the Analysis of Randomized Controlled Trials in Real-World Settings

Harvard University School of Public Health
| Massachusetts
Miguel Hernán, MD, DrPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods to Apply Results from Randomized Trials to Patients in Clinical Practice

Harvard TH Chan School of Public Health
| Massachusetts
Issa J. Dahabreh, MD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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