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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 252 results

Project Title
Project Status
Project Type

Develop Novel Methods to Identify and Characterize Family Relationships from Electronic Health Data

University of Colorado Denver
| Colorado
Toan Ong, PhD, and Lisa Schilling, MD, MSPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Can A/B Testing Be Adapted into an Ethical and Useful Approach to Patient-Centered Outcomes Research?

Memorial Sloan Kettering Cancer Center
| New York
James Flory, MD, MS
Project Status:
Awarded; Contract pending
Project Type:
Research

Data-Adaptive Readmissions Models for Heterogeneous and Longitudinal Data

Regents of the University of Minnesota
| Minnesota
Jared Huling, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

Diagnostic Tools for Quality Improvement of Machine Learning-Based Clinical Decision Support Systems

University of California, San Francisco
| California
Jean Feng, PhD, MS
Project Status:
Awarded; Contract pending
Project Type:
Research

Fast and Robust Weighting Methods for Targeted Comparative Effectiveness Research

President and Fellows of Harvard College
| Massachusetts
Jose Zubizarreta, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

Transportability of Machine Learning-Enabled Confounding Control Methods Across EHR Databases

Brigham and Women's Hospital
| Massachusetts
Richard Wyss, PhD, MS
Project Status:
Awarded; Contract pending
Project Type:
Research

Sensitivity Analysis Methods for Pragmatic Trials with Irregular and Informative Assessment Times

University of Utah
| Utah
Daniel Scharfstein, ScD, MS
Project Status:
Awarded; Contract pending
Project Type:
Research

Statistical Methods for Optimizing Dynamic Patient-Level Treatment and Monitoring Strategies

Rutgers University School of Public Health
| New Jersey
Jason Roy, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving PCOR/CER Study Methodologies in Studies with Different Respondent Types Using IRT

Brown University
| Rhode Island
Roee Gutman, PhD, MS
Project Status:
Awarded; Contract pending
Project Type:
Research

Pragmatic Comparative Effectiveness Using Sequential Multiple Assignment Randomized Trials

University of Pittsburgh at Pittsburgh
| Pennsylvania
Abdus Wahed, PhD, MS, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

Randomized Trials and Their Observational Emulations -- Benchmarking and Join Analysis

President and Fellows of Harvard College
| Massachusetts
Issa Dahabreh, MD, ScD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Causal Mediation Analysis with Machine Learning to Understand Comparative Treatment Effects

New York University
| New York
Ivan Diaz, PhD, MPH, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving Methods for Design and Analysis of CER with Complex Observational Healthcare Data

The University of Texas Southwestern Medical Center
| Texas
Hong Zhu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Robust Longitudinal Causal Inference Methods with Machine Learning

Rutgers, The State University of New Jersey
| New Jersey
Liangyuan Hu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improved Statistical Methods for IV Designs in CER

The Trustees of The University of Pennsylvania
| Pennsylvania
Luke Keele, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Studying Methods for Ethical and Human Subjects Protections Issues in Digital Health PCOR/CER

The Regents of the University of California, San Diego
| California
Camille Nebeker, EdD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Mixed Data Meta-analysis: Integration of Individual Participant and Aggregate Data

The Regents of the University of California, San Francisco
| California
Mi-Ok Kim, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Semantic Data Quality Standards for Multi-Center Clinical Research Studies and Networks

Children's Hospital of Philadelphia
| Pennsylvania
Charles Bailey, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Advanced Computational Approaches for Integrating Data to Assess Effect Heterogeneity

Johns Hopkins Bloomberg School of Public Health
| Maryland
Elizabeth Stuart, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

New Methods for Planning Cluster Randomized Trials to Detect Treatment Effect Heterogeneity

Yale School of Public Health
| Connecticut
Fan Li, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods to Combine and Analyze Data from PRPP-SMART Studies

University of Michigan
| Michigan
Kelley Kidwell, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods to Help Identify Patients with Rare Diseases in Electronic Health Records

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Daniel Herman, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Developing Methods to Analyze Data Missing Due to Death in Cluster Randomized Trials

Trustees of the University of Pennsylvania
| Pennsylvania
Michael Harhay, PhD, MPH, MA, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods for Combining and Analyzing Electronic Health Record Data

University of Pennsylvania
| Pennsylvania
Yong Chen, PhD, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Methods to Generalize Results from Clinical Trials

Brown University
| Rhode Island
Jon Steingrimsson, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

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