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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 38 results

Project Title
Project Status
Project Type

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Carolina Consortium to Improve Blood Pressure Control in Vulnerable Populations

Brody School of Medicine at East Carolina University
| North Carolina
Doyle Cummings, PharmD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Healthcare Visit Recording and Open Notes to Improve the Chronic Illness Care Experience for Older Adults (The CHRONICLE Trial)

Trustees of Dartmouth College
| New Hampshire
Paul Barr, PhD, MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparing Two Ways to Control Blood Pressure after Stroke

Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Help Older Adults Living in Low-Income Housing Maintain Their Health and Independence -- The EPIC Study

Cedars-Sinai
| California
Harriet Aronow, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways for Hospitals to Help Patients Recover During and After Stroke

Vanderbilt University Medical Center
| Tennessee
Kenneth Gaines, MD, MBA
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

What Is the Effect of Adding a Health Coach to Patient-Centered Medical Homes for Managing Multiple Chronic Conditions?

Clinical Directors Network
| New York
Jonathan Tobin, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Community Health Worker and Mobile Health Programs to Help Young Adults with Sickle Cell Disease Transition to Using Adult Healthcare Services -- The COMETS Study

The Childrens' Hospital of Philadelphia
| Pennsylvania
David M. Rubin, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways Primary Care Practices Can Help Patients with Serious Illnesses Get the Care That Matches What Is Important to Them

Oregon Health and Science University
| Oregon
Annette M. Totten, PhD, MPA
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Developing New Methods for Comparing Treatments in Case-Control Studies

Harvard T.H. Chan School of Public Health
| Massachusetts
Goodarz Danaei, MD, MS, DSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Different Data Sets to Test How Well Clinical Prediction Models Work to Predict Patients' Risk of Heart Disease

Tufts Medical Center
| Massachusetts
David M. Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can Early Tracheostomy Improve Recovery and Survival in Patients with Severe Stroke and Breathing Failure? -- The SETPOINT 2 Study

Maine Medical Center
| Maine
David Seder, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Mobile Stroke Treatment with Emergency Room Care -- the BEST-MSU Study

Memorial Hermann Health System, Memorial Hermann-Texas Medical Center
| Texas
James Grotta, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Three Approaches to Improve Diabetes Self-Care among African-American Adults -- The MODEL Study

The University of Tennessee Health Science Center
| Tennessee
James E. Bailey, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Developing Methods to Account for Bias from Unmeasured Sources When Analyzing Time Until a Health Event

Dartmouth College
| New Hampshire
Alistair James O’Malley, BSc (Hons), MS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods to Apply Results from Randomized Trials to Patients in Clinical Practice

Harvard TH Chan School of Public Health
| Massachusetts
Issa J. Dahabreh, MD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Low-Dose versus High-Dose Aspirin to Prevent Problems from Heart Disease -- The ADAPTABLE Study -- A PCORnet® Study

Duke University
| North Carolina
William Schuyler Jones, MD*
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Treat Arm Weakness Due to Stroke

The Ohio State University
| Ohio
Deborah Larsen, PhD, FAPTA, FASAHP^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing a Care Program and Usual Care to Help Patients Transition Home from the Hospital after a Stroke -- The COMPASS Study

Wake Forest University Health Sciences
| North Carolina
Pamela W. Duncan, PhD, PT
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding and Improving Informed Consent for Clinical Trials during Health Emergencies

Emory University
| Georgia
Neal Dickert, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Community Education Program Help Increase Early Hospital Arrival and Ambulance Use for Patients Who Experience Stroke? -- The CEERIAS Study

Northwestern University at Chicago
| Illinois
Shyam Prabhakaran, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Programs to Support Stroke Survivors and Their Caregivers during the Transition Home from the Hospital or a Rehabilitation Facility -- The MISTT Study

Michigan State University
| Michigan
Mathew John Reeves, DVM, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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