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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Displaying 1 - 25 of 58 results

Project Title
Project Status
Project Type

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Sinusitis

Georgetown University Medical Center
| District of Columbia
Daniel Merenstein, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Follow Up after a Child Goes Home from the Hospital -- The FAAN-C Trial

University of Utah
| Utah
Eric Coon, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Does Treating Genital Herpes in Pregnancy Reduce Racial Disparities in Severe Maternal Morbidity? -- The PCORI SMM Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
De-Kun Li, MD, MPH, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Improve COVID-19 Vaccination Rates at Long-Term Care Centers -- The ENSPIRE Study

Kaiser Foundation Health Plan of Washington (Kaiser Permanente Washington Health Research Institute)
| California
Clarissa Hsu, PhD, MA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Increase Confidence in COVID-19 Vaccines among Long-Term Care Workers -- The CONFIDENT Trial

Trustees of Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, MSc
Project Status:
In progress; Data collected
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Treatment for Opioid Use Disorder before and during the COVID-19 Pandemic

Boston VA Research Institute, Inc.
| Massachusetts
Nicholas Livingston, PhD and Risa Weisberg, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Telehealth and In-Person Care for Patients with Chronic Conditions

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Programs to Train Staff to Reduce the Spread of COVID-19 in Nursing Homes

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Jennifer L. Kraschnewski, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing How State and Local COVID-19 Policies Affect Patient-Reported Outcomes

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Does the Stress First Aid Program Improve Well-Being among Healthcare Workers during the COVID-19 Pandemic? -- The COVER-HCW Project

RAND Corporation
| California
Lisa S. Meredith, PhD
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research

Comparative Effectiveness of Single-Site and Scattered-Site Permanent Supportive Housing on Patient-Centered and COVID-19 Related Outcomes for People Experiencing Homelessness

University of Southern California
| California
Benjamin Henwood, PhD, MA, MSW
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Ways to Monitor Patients with COVID-19 at Home -- COVID Watch

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research

Comparing Two Ways to Deliver Remote Mental Health Support during the COVID-19 Pandemic

The Research Foundation For The State University of New York
| New York
Yu-Ping Chang, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Programs to Decrease HIV Risk among African-Born Black Women

Brigham and Women's Hospital
| Massachusetts
Bisola Ojikutu, MD, MPH
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Improve Pre-Exposure Prophylaxis (PrEP) Use for HIV Prevention

Public Health Foundation Enterprises, Inc.
| California
Albert Liu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Monitor Patients with Multiple Chronic Conditions after They Return Home from the Hospital for an Infection -- The ACCOMPLISH Study

UPMC Center for High-Value Health Care
| Pennsylvania
Dr. Kalpana Char, MD*
Project Status:
In progress; Recruiting
Project Type:
Research

Improving Antibiotic Prescribing in Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Do Public Deliberation Methods Help Improve the Informed Consent Process for Research on Sensitive Topics?

Trustees of Indiana University
| Indiana
Amelia S. Knopf, PhD, MPH, BSN
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Admit Children to Hospitals

Dartmouth-Hitchcock Clinic^
| New Hampshire
JoAnna Leyenaar, MD, MPH, MS
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Ways to Increase HPV Testing for Cervical Cancer Screening

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Chun Chao, PhD, MS
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Ways to Help African-American and Latino Patients with HIV to Receive and Retain Care

Johns Hopkins School of Medicine
| Maryland
Kathleen Page, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Treatments for Dental Cavities in Older Adults Living in Low-Income Housing

Case Western Reserve University
| Ohio
Suchitra Nelson, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

What Is the Effect of Adding a Health Coach to Patient-Centered Medical Homes for Managing Multiple Chronic Conditions?

Clinical Directors Network
| New York
Jonathan Tobin, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

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