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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Displaying 1 - 25 of 32 results

Project Title
Project Status
Project Type

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients Who Are at Risk for Heart Disease

Mayo Clinic
| Minnesota
Rozalina McCoy, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Helping Patients Achieve Kidney Transplants through Health System Change

Duke University
| North Carolina
Leigh Ebony Boulware, MD, MPH, FACP
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Approaches to Care Coordination for Patients with Multiple Health Needs

HealthPartners Institute
| Minnesota
Leif I. Solberg, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Help Patients with Chronic Kidney Disease and Their Care Partners Choose among Treatment Options -- The DART Study

Tufts University
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Provide Palliative Care to Older Adults with Serious Illness

New York University School of Medicine
| New York
Keith S. Goldfeld, DrPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Ways to Encourage and Improve End-of-Life Care Planning

Duke University
| North Carolina
Kimberly Johnson, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Identifying Barriers to Telehealth Home-Based Palliative Care for Patients with Serious Illness -- The HomePal Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Huong Q. Nguyen, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

A New Statistical Method for Designing Stepped-Wedge Cluster Trials

University of Texas Southwestern Medical Center at Dallas
| Texas
Song Zhang, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Approaches to Improve Black Patients’ Chances of Getting Live Donor Kidney Transplants

Beth Israel Deaconess Medical Center
| Massachusetts
James R. Rodrigue, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Providing at-Home Kidney Disease Care for Native Americans in New Mexico

University of New Mexico Health Sciences Center
| New Mexico
Vallabh O. Shah, PhD
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results

Comparing the Benefits and Harms of Different Long-Term Treatments for Blood Clots -- The DARE Warfarin Study

Brigham and Women's Hospital
| Massachusetts
Katsiaryna Bykov, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Treatment Strategies to Prevent Future Blood Clots among Patients Who Received at Least Three Months of Blood Thinners -- The ALTERNATIVE Study

University of California, San Francisco
| California
Margaret Fang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Three Approaches to Improve Diabetes Self-Care among African-American Adults -- The MODEL Study

The University of Tennessee Health Science Center
| Tennessee
James E. Bailey, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Ways to Improve Dialysis Session Stability

University of Michigan
| Michigan
Tiffany Veinot, MLIS, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Ways to Reduce High Blood Pressure in Patients from Different Racial and Ethnic Groups -- The RICH LIFE Study

Johns Hopkins University
| Maryland
Lisa A. Cooper, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways of Combining Behavioral Health Care and Primary Care for Adults

University of Vermont and State Agricultural College
| Vermont
Benjamin Littenberg, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Testing a Program to Help Patients Prepare for Kidney Failure Treatment -- The PREPARE NOW Study

Duke University
| North Carolina
Leigh E. Boulware, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Designing and Testing a Visit Planner to Help Patients Address Their Top Concerns during Healthcare Visits

Kaiser Foundation Research Institute
| California
Richard W. Grant, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Self-Management of Urinary Symptoms Using a Probiotic in People with Spinal Cord Injuries, Spina Bifida, and Multiple Sclerosis

MedStar Health Research Institute
| Maryland
Suzanne Groah, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Depression among Patients with Kidney Failure Receiving Hemodialysis -- The ASCEND Study

University of Washington
| Washington
Rajnish Mehrotra, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Improve Quality of Life for Patients with Kidney Disease and Their Caregivers

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Nasrollah Ghahramani, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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