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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 41 results

Project Title
Project Status
Project Type

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD

Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Using Technology to Improve Maternal Mental Health and Substance Use Disorder Screening and Treatment

Medical University of South Carolina
| South Carolina
Constance Guille, MD, MSCR
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Recruiting
Project Type:
Research

Culturally Adapted Online Couples Communication Program for Latina Breast Cancer Patients

University of South Florida
| Florida
Dinorah Martinez Tyson, PhD, MPH, MA
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Improve Mental Health among Youth with Disabilities -- The BEST Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Provide Maternal Mental Health Treatment to Women Who Are Black or of African Descent Living in Washington, DC

Children's Research Institute
| District of Columbia
Catherine Limperopoulos, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing the Effectiveness of Behavioral Health Supports for Publicly Insured Perinatal Women

UPMC Center for High-Value Health Care
| Pennsylvania
Ellen Beckjord, PhD, MPH
Project Status:
Awarded; Contract not executed
Project Type:
Research

Comparing Two Ways to Deliver Remote Mental Health Support during the COVID-19 Pandemic

The Research Foundation For The State University of New York
| New York
Yu-Ping Chang, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Anxiety in Patients Who Go to the Emergency Room with Low-Risk Chest Pain

Trustees of Indiana University
| Indiana
Paul Musey, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Treat Anxiety in Youth

Children's Hospital Los Angeles
| California
Bradley S. Peterson, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Anxiety Disorders among Children and Adolescents

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
John T. Walkup, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Pregnancy Care Programs for Preventing Premature Births

University of California, San Francisco
| California
Miriam Kuppermann, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Methods for Treating Depression and Anxiety among Pregnant and Postpartum Women

Sinai Health System (Canada)
Daisy Singla, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two School Behavioral Health Programs to Improve Students' Academic Performance and Mental Health

University of South Carolina
| South Carolina
Mark Weist, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Help Sexual and Gender Minority Male Survivors of Sexual Abuse Reduce Distress and Engage in Treatment

Yale University
| Connecticut
Joan Cook, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Remote Cognitive Behavior Therapy for Major Depression in Primary Care

University of South Florida
| Florida
Robert Bossarte, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Depression Prevention Programs for Teens -- The Path 2 Purpose Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Programs to Treat Patients with Inflammatory Bowel Disease and Behavioral Health Conditions

UPMC Center for High-Value Health Care
| Pennsylvania
Eva Szigethy, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Online and In-Person Cognitive Behavioral Therapy in Youth with Anxiety Disorders -- The Kids FACE FEARS Study

Boston Medical Center Corporation
| Massachusetts
Donna Pincus
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Two Ways to Treat Youth with Anxiety or Obsessive-Compulsive Disorder (OCD)

Emma Pendleton Bradley Hospital
| Rhode Island
Jennifer Freeman, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

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