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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Displaying 1 - 25 of 95 results

Project Title
Project Status
Project Type

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD

Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Using Technology to Improve Maternal Mental Health and Substance Use Disorder Screening and Treatment

Medical University of South Carolina
| South Carolina
Constance Guille, MD, MSCR
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Preventing Suicidal Behavior with Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University
| Maryland
Holly Wilcox, PhD, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

LIVE-SMART: Liver cirrhosis interventions for fall prevention: a sequential, multiple assignment randomized trial

University of Michigan
| Michigan
Elliot Tapper, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Healthcare Visit Recording and Open Notes to Improve the Chronic Illness Care Experience for Older Adults (The CHRONICLE Trial)

Trustees of Dartmouth College
| New Hampshire
Paul Barr, PhD, MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Community-Based, Family-Centered, Trauma-Informed Approach to Timely Detection and Management of Early Postpartum Hypertension

Yale School of Public Health
| Connecticut
Rafael Perez-Escamilla, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

Preventing Suicide among Sexual and Gender Diverse Young Adults in Primary Care in Texas

UT Southwestern Medical Center
| Texas
Elizabeth Arnold, PhD, MSW
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Prevent Suicide among Alaska Native Young People -- The BeWeL Study

RAND Corporation
| Pennsylvania
Elizabeth D'Amico, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia

Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Culturally Adapted Online Couples Communication Program for Latina Breast Cancer Patients

University of South Florida
| Florida
Dinorah Martinez Tyson, PhD, MPH, MA
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Improve Mental Health among Youth with Disabilities -- The BEST Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Provide Maternal Mental Health Treatment to Women Who Are Black or of African Descent Living in Washington, DC

Children's Research Institute
| District of Columbia
Catherine Limperopoulos, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing the Effectiveness of Behavioral Health Supports for Publicly Insured Perinatal Women

UPMC Center for High-Value Health Care
| Pennsylvania
Ellen Beckjord, PhD, MPH
Project Status:
Awarded; Contract not executed
Project Type:
Research

Comparing Two Ways to Deliver Remote Mental Health Support during the COVID-19 Pandemic

The Research Foundation For The State University of New York
| New York
Yu-Ping Chang, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Offer Remote Therapy for Depressive Symptoms in People with Heart Disease

University of Kentucky
| Kentucky
Debra Moser, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Help Older Adults Living in Low-Income Housing Maintain Their Health and Independence -- The EPIC Study

Cedars-Sinai
| California
Harriet Aronow, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Approaches to Care Coordination for Patients with Multiple Health Needs

HealthPartners Institute
| Minnesota
Leif I. Solberg, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Treat Anxiety in Youth

Children's Hospital Los Angeles
| California
Bradley S. Peterson, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Pregnancy Care Programs for Preventing Premature Births

University of California, San Francisco
| California
Miriam Kuppermann, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Methods for Treating Depression and Anxiety among Pregnant and Postpartum Women

Sinai Health System (Canada)
Daisy Singla, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

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