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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 18 of 18 results

Project Title
Project Status
Project Type

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD

Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Using Technology to Improve Maternal Mental Health and Substance Use Disorder Screening and Treatment

Medical University of South Carolina
| South Carolina
Constance Guille, MD, MSCR
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Preventing Suicidal Behavior with Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University
| Maryland
Holly Wilcox, PhD, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

Community-Based, Family-Centered, Trauma-Informed Approach to Timely Detection and Management of Early Postpartum Hypertension

Yale School of Public Health
| Connecticut
Rafael Perez-Escamilla, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparing Two Suicide Prevention Programs for Young People following an ER Visit

University of California, Los Angeles
| California
Joan Asarnow, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Preventing Suicide among Sexual and Gender Diverse Youth

UT Southwestern Medical Center
| Texas
Elizabeth Arnold, PhD, MSW
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Prevent Suicide among Autistic Youth

The University of North Carolina at Chapel Hill
| North Carolina
Brenna Maddox, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Prevent Suicide among Alaska Native Young People -- The BeWeL Study

RAND Corporation
| Pennsylvania
Elizabeth D'Amico, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
Awarded; In progress
Project Type:
Research
Has Results

Comparing Two Ways to Provide Safety Planning Follow-Up Support for Adults and Teens at Risk of Suicide

St. Luke's Health System
| Idaho
Anna K. Radin, DrPH, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Inpatient Versus Outpatient Settings for Treating Teens after a Suicidal Event

Cincinnati Children's Hospital Medical Center
| Ohio
Drew Barzman, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways to Coordinate Care for Patients after Trauma

University of Washington
| Washington
Douglas Zatzick, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Two Ways to Treat Youth with Anxiety or Obsessive-Compulsive Disorder (OCD)

Emma Pendleton Bradley Hospital
| Rhode Island
Jennifer Freeman, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Effect of High-Deductible Health Plans on Healthcare Use and Out-of-Pocket Costs for People with Bipolar Disorder

Harvard Pilgrim Health Care, Inc.
| Massachusetts
James Franklin Wharam, MB, BCh, BAO, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Ask Patients about Sexual Orientation and Gender Identity in the Emergency Room -- The EQUALITY Study

Brigham and Women’s Hospital^
| Massachusetts
Adil Haider, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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