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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 39 results

Project Title
Project Status
Project Type

Cardiac Resynchronization Therapy Using His/Left Bundle Pacing vs. Left Ventricular Epicardial Pacing in Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Community-Based, Family-Centered, Trauma-Informed Approach to Timely Detection and Management of Early Postpartum Hypertension

Yale School of Public Health
| Connecticut
Rafael Perez-Escamilla, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

THRIVE: Trajectories of Recovery after Intravenous Propofol vs inhaled VolatilE anesthesia

Regents of the University of Michigan
| Michigan
Sachin Kheterpal, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Ways to Monitor Patients with COVID-19 at Home -- COVID Watch

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Ways to Monitor Glucose among People with Type 2 Diabetes

HealthPartners Institute
| Minnesota
Richard Bergenstal, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Prevent Severe Hypoglycemia in Patients with Type 2 Diabetes

Kaiser Foundation Health Plan of Washington
| Washington
James Ralston, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Programs for Managing Hearing Loss among Older Adults in Assisted Living Facilities

University of Pittsburgh
| Pennsylvania
Catherine Palmer, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Obtain Hearing Aids for People with Age-Related Hearing Loss

Northwestern University
| Illinois
Sumitrajit Dhar, PhD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Surgery and Medical Management for Treating Diverticulitis -- The COSMID Study

University of Washington
| Washington
David Flum, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Developing Methods for Estimating Effects of More Than Two Treatment Options

Rutgers, The State University of New Jersey
| New Jersey
Liangyuan Hu, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Perform Catheter Ablation to Treat Abnormal Heart Rhythms

The Regents of the University of California, San Francisco
| California
Gregory Marcus, MD, MAS
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Hair Removal Treatments for Adolescents with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter Minneci, MD
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Home- Versus Clinic-Based Phototherapy for the Treatment of Psoriasis -- The LITE Study

University of Pennsylvania
| Pennsylvania
Joel Mitchell Gelfand, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Improving Learning Healthcare Systems Using Randomization Methods

Dartmouth College
| New Hampshire
Tor D. Tosteson, ScD, BA, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Can Early Tracheostomy Improve Recovery and Survival in Patients with Severe Stroke and Breathing Failure? -- The SETPOINT 2 Study

Maine Medical Center
| Maine
David Seder, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Identify Sleep Apnea in People with Traumatic Brain Injury during Inpatient Rehabilitation

Tampa VA Research and Education Foundation
| Florida
Risa Nakase-Richardson, PhD, FACRM, FNAN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Home, Clinic, and Kiosk Blood Pressure Checks for Diagnosing High Blood Pressure -- The BP-CHECK Study

Kaiser Permanente Washington Health Research Institute^
| Washington
Beverly B. Green, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing ECT and Ketamine in Adults with Treatment-Resistant Depression – The ELEKT-D Study

Cleveland Clinic Foundation
| Ohio
Amit Anand, MD^
Project Status:
In progress; Data collected
Project Type:
Research

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